Penetration of daptomycin in cerebrospinal fluid during pneumococcal meningitis.

Date publication

janvier 2026

Journal

The Journal of antimicrobial chemotherapy

Auteurs

Membres identifiés du Cancéropôle Est :
Dr FOURNEL Isabelle

Tous les auteurs :
Chavanet P, Matheux A, Sixt T, Barbet J, Nau R, Guerard P, Fournel I, Mourvillier B, Blot M, Piroth L

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/41556125

Résumé

There are few data on the penetration of daptomycin into the cerebrospinal fluid (CSF) of patients with bacterial meningitis. This ancillary study of the AddaMap trial aimed to assess the CSF penetration of intravenous daptomycin in 13 patients with pneumococcal meningitis.

Mots clés

Humans, Daptomycin, pharmacokinetics, Meningitis, Pneumococcal, drug therapy, Anti-Bacterial Agents, pharmacokinetics, Middle Aged, Male, Female, Aged, Adult, Cerebrospinal Fluid, chemistry, Plasma, chemistry, Hospitals, University, Administration, Intravenous, Aged, 80 and over, Young Adult

Référence

J Antimicrob Chemother. 2026 01 19;81(2):