Fiche publication
Date publication
décembre 2025
Journal
Beilstein journal of nanotechnology
Auteurs
Membres identifiés du Cancéropôle Est :
Dr MERTZ Damien
,
Pr ALEM-MARCHAND Halima
Tous les auteurs :
Louaguef D, Medjahdi G, Diliberto S, Seemann KM, Gries T, Bizeau J, Mertz D, Gaffet E, Alem H
Lien Pubmed
Résumé
Superparamagnetic iron oxide nanoparticles (SPIONs) offer promising applications in nanomedicine due to their appealing properties. Their magnetic and magnetic hyperthermia properties are considered as relevant tools for low invasive cancer therapeutic applications. In this work, we report on the synthesis of polyhedral core-shell SPIONs. Their size was tuned to improve their magnetic properties. Furthermore, by hybridizing into a core-shell inorganic/inorganic structure, the nanoparticles can achieve significantly improved magnetic-to-thermal energy conversion efficiency (at least tenfold). The designed core NPs are composed of a ZnFeO core and a MnFeO shell. Their size and morphology were determined by transmission electron microscopy, Fourier-transform infrared spectroscopy was used to investigate their chemical composition. The iron oxide phase was confirmed by Mössbauer analysis, and the magnetic properties were studied to select the ideal size for magnetic hyperthermia application.
Mots clés
core–shell nanoparticles, magnetic hyperthermia, magnetic properties
Référence
Beilstein J Nanotechnol. 2025 12 15;16:2285-2295