Fiche publication


Date publication

décembre 2025

Journal

Beilstein journal of nanotechnology

Auteurs

Membres identifiés du Cancéropôle Est :
Dr MERTZ Damien , Pr ALEM-MARCHAND Halima


Tous les auteurs :
Louaguef D, Medjahdi G, Diliberto S, Seemann KM, Gries T, Bizeau J, Mertz D, Gaffet E, Alem H

Résumé

Superparamagnetic iron oxide nanoparticles (SPIONs) offer promising applications in nanomedicine due to their appealing properties. Their magnetic and magnetic hyperthermia properties are considered as relevant tools for low invasive cancer therapeutic applications. In this work, we report on the synthesis of polyhedral core-shell SPIONs. Their size was tuned to improve their magnetic properties. Furthermore, by hybridizing into a core-shell inorganic/inorganic structure, the nanoparticles can achieve significantly improved magnetic-to-thermal energy conversion efficiency (at least tenfold). The designed core NPs are composed of a ZnFeO core and a MnFeO shell. Their size and morphology were determined by transmission electron microscopy, Fourier-transform infrared spectroscopy was used to investigate their chemical composition. The iron oxide phase was confirmed by Mössbauer analysis, and the magnetic properties were studied to select the ideal size for magnetic hyperthermia application.

Mots clés

core–shell nanoparticles, magnetic hyperthermia, magnetic properties

Référence

Beilstein J Nanotechnol. 2025 12 15;16:2285-2295