Fiche publication
Date publication
décembre 2025
Journal
Nature neuroscience
Auteurs
Membres identifiés du Cancéropôle Est :
Dr YALCIN CHRISTMANN Ipek
Tous les auteurs :
Finn DP, McGuire BE, Beggs S, Boerner KE, Davis KD, Defrin R, De Koninck Y, Devan H, Donovan R, Fetter E, Flor H, Fullen BM, Healy CR, Keogh E, Kuner R, Kunz M, Lane RM, Lautenbacher S, Mayer EA, Mogil JS, O'Mahony SM, O'Sullivan K, Riordan L, Salter MW, Scarlatti F, Shorten G, Sluka KA, Stinson JN, Vowles KE, Walker SM, Yalcin I, Roche M
Lien Pubmed
Résumé
Sex and gender are important variables in research, but they are inconsistently explored. The international PAINDIFF Network makes 13 recommendations for studying sex and gender as variables in pain research, which are applicable across the spectrum of biopsychosocial research. Five universal recommendations apply to the majority of research studies: (1) include males and females as standard practice, (2) account for sex in randomization or counterbalancing and testing order, (3) power for sex differences when sex is a primary experimental variable, (4) include detailed reporting of experimental design, and (5) conduct sex-disaggregated analysis and reporting. Three additional recommendations specifically for preclinical studies and five additional recommendations for human and clinical studies are included. Recommendations for stakeholders, such as editors, reviewers, funding bodies and policymakers, have also been developed. Wide adoption and implementation of these recommendations will reduce variability, improve reproducibility and enhance the translatability of research findings within and beyond the field of pain.
Référence
Nat Neurosci. 2025 12 29;:
