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Date publication

novembre 2025

Journal

European journal of cancer (Oxford, England : 1990)

Auteurs

Membres identifiés du Cancéropôle Est :
Pr PETIT Thierry


Tous les auteurs :
Pujol P, Roca L, Lortholary A, Lasset C, Crivelli L, Berthet P, Tennevet I, Petit T, Chabbert-Buffet N, Gesta P, Saule C, Chiesa J, Nguyen TD, Mailliez A, Callet NA, Noguès C, Dreyfus H, Delnatte C, Prieur F, Gladieff L, Ingster O, Galibert V, Lemonnier J, Delaloge S

Résumé

Women carrying a germline BRCA1 or BRCA2 mutation (gBRCAm) have a 70 % lifetime risk of breast cancer (BC). Aromatase inhibitors (AI) decrease BC incidence in high-risk populations but have not been specifically assessed in gBRCAm carriers.

Mots clés

Aromatase inhibitors, BRCA mutation, Breast cancer, Chemoprevention, Letrozole

Référence

Eur J Cancer. 2025 11 7;231:116101