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Date publication

novembre 2025

Journal

Annals of oncology : official journal of the European Society for Medical Oncology

Auteurs

Membres identifiés du Cancéropôle Est :
Pr BASTIE Jean-Noël , Dr BOLOGNA Serge , Pr OLIVIER Pierre


Tous les auteurs :
Michot JM, Bologna S, Bastie JN, Borght TV, Brière J, Ribrag V, Bommier C, Peyrade F, Lebras L, Damaj G, Coso D, Sibon D, Bonnet C, Morschhauser F, Ghesquières H, Fruchart C, Soussain C, Becker S, Olivier P, Julian A, Molina T, Haioun C, Tilly H

Résumé

Preliminary reports suggest interim positron emission tomography (PET) could drive treatment duration in limited-stage diffuse large B-cell lymphoma (DLBCL). This phase 3 randomised study in front-line therapy for DLBCL patients with adjusted-age IPI (aaIPI) risk = 0, evaluates an experimental PET-response adapted approach using PET response after 2 cycles of R-CHOP to de-escalate treatment duration.

Référence

Ann Oncol. 2025 11 17;: