Aortic atherosclerotic plaques are more thrombogenic than carotid and femoral plaques: the role of fibrillar collagen.

Fiche publication

Date publication

octobre 2025

Journal

Atherosclerosis

Auteurs

Membres identifiés du Cancéropôle Est :
Dr MANGIN Pierre

Tous les auteurs :
Feng M, Thevenot A, Kuntz S, Liu C, Schellenberg C, Charle L, Brouard N, Schaeffer C, Ortiz SJ, Cosemans JMEM, Chakfé N, Mangin PH

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/41172703

Résumé

Atherothrombosis is the leading cause of mortality worldwide, responsible for more deaths than any other condition. Although the determinants of atherothrombosis are well established, the thrombogenic potential of atherosclerotic plaques in different arterial territories remains unexplored. This study aimed to perform an in-depth characterization of plaques from aortic, carotid and femoral arteries by comparing their intrinsic composition and thrombogenicity.