Fiche publication


Date publication

octobre 2025

Journal

PloS one

Auteurs

Membres identifiés du Cancéropôle Est :
Pr TROJAK Benoît , Dr DEMINA Anastasia


Tous les auteurs :
Demina A, Petit B, Trojak B

Résumé

Alcohol use disorder (AUD) is a chronic condition linked to allostatic neuroadaptations in the brain's reward circuitry, leading to compulsive and automatized alcohol use in response to craving or negative affect. There are only a few treatment options for AUD, and their efficacy and tolerance profiles remain suboptimal. New AUD management strategies are actively being investigated, and among these, non-invasive brain stimulation (NIBS) interventions. We are planning to conduct a systematic review and network meta-analysis to simultaneously compare different NIBS strategies for AUD, and the present protocol aims to document our methodological approaches and a priori decisions.

Mots clés

Humans, Systematic Reviews as Topic, Alcoholism, therapy, Network Meta-Analysis as Topic, Brain, physiopathology, Randomized Controlled Trials as Topic, Transcranial Direct Current Stimulation, methods, Treatment Outcome, Transcranial Magnetic Stimulation, methods, Craving

Référence

PLoS One. 2025 10 7;20(10):e0332857