Fiche publication
Date publication
octobre 2025
Journal
Annales de pathologie
Auteurs
Membres identifiés du Cancéropôle Est :
Pr LEBRE Anne-Sophie
Tous les auteurs :
Tauziède-Espariat A, Métais A, Sassi F, Pucelle N, Mandoula M, Dababou Z, Carnes N, Berthaud C, Brissez L, Saffroy R, Lebre AS, Servant E, Varlet P
Lien Pubmed
Résumé
The 2021 World Health Organisation (WHO) classification of tumours of the central nervous system introduced molecular biomarkers (homozygous deletion of CDKN2A/B and TERT promoter mutation) in the grading of meningiomas. Since, the cIMPACT-NOW consortium has proposed a new prognostic algorithm (published in the update 8), integrating epigenetic and genetic data. The aim of the study was to report on the experience of the neuropathology department of Sainte-Anne Hospital in integrating this algorithm into the gradingof meningiomas.
Mots clés
CDKN2A/B, Grade, Meningioma, Methylation profile, Méningiome, Méthylome, OMS, WHO, pTERT
Référence
Ann Pathol. 2025 10 13;:
