Fiche publication


Date publication

novembre 2025

Journal

EClinicalMedicine

Auteurs

Membres identifiés du Cancéropôle Est :
Pr GUILLEMIN Francis


Tous les auteurs :
Grammoustianou M, Maccarone S, Gillanders E, Menvielle G, Preau M, Ginguene S, Everhard S, Delpierre C, Guillemin F, Vaz-Luis I, Franzoi MA

Résumé

Diverse population inclusion in clinical research is essential for generating high-quality, generalizable data that promotes health equity. However, clinical research often underrepresents elderly individuals, minoritised ethnicities, and marginalized socio-demographic groups. Implicit and explicit biases among healthcare providers can create barriers to equitable participation in clinical trials, affecting patient care, clinical outcomes, and provider-patient trust. Bias-focused interventions have been reported, yet methodological inconsistencies and limited generalizability of studies hinder their effectiveness. This systematic review synthesizes global evidence on interventions designed to address healthcare provider biases, identifying intervention components, trends, outcomes assessed and gaps in the current literature.

Mots clés

Clinical trials, Cultural competence, Digital, Disparities, Explicit bias, Healthcare, Healthcare providers, Implicit bias, Interventions

Référence

EClinicalMedicine. 2025 11;89:103513