Fiche publication
Date publication
septembre 2014
Journal
JACC. Cardiovascular imaging
Auteurs
Membres identifiés du Cancéropôle Est :
Pr COCHET Alexandre
Tous les auteurs :
van Kranenburg M, Magro M, Thiele H, de Waha S, Eitel I, Cochet A, Cottin Y, Atar D, Buser P, Wu E, Lee D, Bodi V, Klug G, Metzler B, Delewi R, Bernhardt P, Rottbauer W, Boersma E, Zijlstra F, van Geuns RJ
Lien Pubmed
Résumé
The aim of this study was to evaluate the value of microvascular obstruction (MO) and infarct size as a percentage of left ventricular mass (IS%LV), as measured by contrast-enhanced cardiac magnetic resonance, in predicting major cardiovascular adverse events (MACE) at 2 years in patients with ST-segment elevation myocardial infarction reperfused by primary percutaneous coronary intervention. Individual data from 1,025 patients were entered into the pooled analysis. MO was associated with the occurrence of MACE, defined as a composite of cardiac death, congestive heart failure, and myocardial re-infarction (adjusted hazard ratio: 3.74; 95% confidence interval: 2.21 to 6.34). IS%LV ≥25% was not associated with MACE (adjusted hazard ratio: 0.90; 95% confidence interval: 0.59 to 1.37). The authors conclude that MO is an independent predictor of MACE and cardiac death, whereas IS%LV is not independently associated with MACE.
Mots clés
Aged, Coronary Circulation, Female, Heart Failure, mortality, Heart Ventricles, pathology, Humans, Magnetic Resonance Imaging, Male, Microcirculation, Middle Aged, Myocardial Infarction, diagnosis, Myocardium, pathology, No-Reflow Phenomenon, diagnosis, Percutaneous Coronary Intervention, adverse effects, Predictive Value of Tests, Recurrence, Risk Assessment, Risk Factors, Time Factors, Treatment Outcome
Référence
JACC Cardiovasc Imaging. 2014 Sep;7(9):930-9
