Fiche publication
Date publication
septembre 2025
Journal
Annual review of virology
Lien Pubmed
Résumé
Plant viruses, which can cause devastating plant diseases, are obligate intracellular pathogens that replicate their genomes inside cells and spread infection by cell-to-cell movement through cell wall nanochannels called plasmodesmata (PD). Double-stranded RNA, which occurs as a replication intermediate of RNA viruses, triggers adaptive and innate host defense responses that are controlled by virus-encoded effector proteins. These defenses include RNA silencing and RNA decay, which target viral RNA and inhibit virus accumulation, and pattern-triggered immunity (PTI), which targets PD and inhibits virus movement. This review discusses the role of RNA silencing, RNA decay, PTI, and effector-triggered immunity as antiviral defense mechanisms, how they are interrelated, and how viruses interact with these mechanisms to ensure their successful replication and spread throughout the plant organism.
Mots clés
RNA silencing, pattern-triggered immunity, plant, plasmodesmata, recognition, virus
Référence
Annu Rev Virol. 2025 09;12(1):421-449
