Fiche publication


Date publication

octobre 2025

Journal

Journal of ovarian research

Auteurs

Membres identifiés du Cancéropôle Est :
Dr AMIOT Clotilde , Pr ROUX Christophe


Tous les auteurs :
Frontczak S, Zver T, Pretalli JB, Blagosklonov O, Amiot C, Roux C, Grenouillet F, Scheffler F

Résumé

Ovarian tissue autotransplantation is currently the only proven technique for reusing ovarian tissue after fertility preservation by ovarian tissue cryopreservation. However, one of its limitations relates to the quality of the grafts, both in terms of the number of surviving follicles and the quality of the stromal environment, which is essential for follicular development and graft revascularization. The aim of this study was to validate a technique for characterizing and functionally qualifying ovarian tissue in order to identify cell sub-populations of interest.

Mots clés

Fertility preservation, Multicolor flow cytometry, Ovarian tissue, Ovarian tissue cryopreservation, Qualification, Stromal cell

Référence

J Ovarian Res. 2025 10 1;18(1):215