Fiche publication
Date publication
septembre 2025
Journal
Journal of neurology, neurosurgery, and psychiatry
Auteurs
Membres identifiés du Cancéropôle Est :
Pr DE SEZE Jérôme
Tous les auteurs :
Gavoille A, Nourredine M, Rollot F, Casey R, Mathey G, Kerbrat A, Ciron J, De Sèze J, Stankoff B, Maillart E, Ruet A, Labauge P, Kwiatkowski A, Zephir H, Papeix C, Defer G, Lebrun-Frenay C, Moreau T, Laplaud DA, Berger E, Clavelou P, Thouvenot E, Heinzlef O, Pelletier J, Al Khedr A, Casez O, Bourre B, Wahab A, Magy L, Moulin S, Camdessanché JP, Doghri I, Sarov M, Hankiewicz K, Pottier C, Dos Santos A, Manchon E, Tchikviladze M, Rabilloud M, Subtil F, Vukusic S
Lien Pubmed
Résumé
BackgroundTarget trial emulation (TTE) offers a formal framework for causal inference using observational data, but its validity must be evaluated in each research domain by replicating randomised clinical trials (RCTs). We aimed to replicate eight RCTs evaluating the efficacy of disease-modifying therapies (DMTs) in multiple sclerosis (MS) using French registry data.
Mots clés
MULTIPLE SCLEROSIS, NEUROEPIDEMIOLOGY, STATISTICS
Référence
J Neurol Neurosurg Psychiatry. 2025 09 4;:
