Fiche publication
Date publication
septembre 2025
Journal
European journal of breast health
Auteurs
Membres identifiés du Cancéropôle Est :
Pr MATHELIN Carole
Tous les auteurs :
Buttignol M, Bouche C, Chrétien M, Taris N, Ozmen T, Mathelin C
Lien Pubmed
Résumé
Hereditary hemochromatosis and breast cancer are two major public health problems. The gene variants C282Y and H63D, responsible for most cases of hemochromatosis, may contribute to carcinogenesis via iron overload, oxidative stress, and hormonal modulation. The aim of this study was to evaluate the association between variants and breast cancer risk and propose a personalized surveillance strategy.
Mots clés
Breast cancer, genetic predisposition, hemochromatosis, iron overload, meta-analysis
Référence
Eur J Breast Health. 2025 09 5;:
