Endotoxin removal by the OXIRIS filter for cardiogenic shock requiring veno-arterial extra-corporeal life support: the ECMORIX randomized controlled trial.

Date publication

juillet 2025

Journal

Annals of intensive care

Auteurs

Membres identifiés du Cancéropôle Est :
Dr PAIS DE BARROS Jean-Paul , Pr MASSON David

Tous les auteurs :
Nguyen M, Alvarez M, Evezard C, Berthoud V, Leleu D, Pais-De-Barros JP, Bouchot O, Abou-Arab O, Bouhemad B, Masson D, Gautier T, Guinot PG

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/40627256

Résumé

Most severe cardiogenic shock requires veno-arterial extracorporeal membrane oxygenation (VA-ECMO). The OXIRIS filter, has shown potential in reducing lipopolysaccharide (LPS) levels. Our objective was to compare the efficacy of the OXIRIS filter versus the ST-150 filter in reducing LPS plasma concentration. We hypothesized that the OXIRIS filter would reduce the endotoxin burden.

Mots clés

Cardiogenic-shock, Critical care, ECMO, Endotoxemia, Inflammation, Translocation

Référence

Ann Intensive Care. 2025 07 8;15(1):92