Fiche publication
Date publication
juillet 2025
Journal
Heart (British Cardiac Society)
Auteurs
Membres identifiés du Cancéropôle Est :
Pr ROSSIGNOL Patrick
Tous les auteurs :
Wang N, Xhaard C, Baudry G, Monzo L, Bozec E, Duarte K, Rossignol P, Zannad F, Lund L, Girerd N
Lien Pubmed
Résumé
Myeloperoxidase (MPO), a neutrophil-derived enzyme, is associated with oxidative stress and inflammation, which contribute to the pathophysiology of heart failure with preserved ejection fraction (HFpEF). Bioactive MPO causes vascular dysfunction and accumulation of serum uric acid (SUA). We investigated the association of plasma MPO and SUA with echocardiographic variables in a populational setting.
Mots clés
Echocardiography, Heart Failure, Diastolic, Inflammation
Référence
Heart. 2025 07 11;: