Fiche publication


Date publication

juillet 2025

Journal

Heart (British Cardiac Society)

Auteurs

Membres identifiés du Cancéropôle Est :
Pr ROSSIGNOL Patrick


Tous les auteurs :
Wang N, Xhaard C, Baudry G, Monzo L, Bozec E, Duarte K, Rossignol P, Zannad F, Lund L, Girerd N

Résumé

Myeloperoxidase (MPO), a neutrophil-derived enzyme, is associated with oxidative stress and inflammation, which contribute to the pathophysiology of heart failure with preserved ejection fraction (HFpEF). Bioactive MPO causes vascular dysfunction and accumulation of serum uric acid (SUA). We investigated the association of plasma MPO and SUA with echocardiographic variables in a populational setting.

Mots clés

Echocardiography, Heart Failure, Diastolic, Inflammation

Référence

Heart. 2025 07 11;: