Fiche publication


Date publication

juin 2025

Journal

The lancet. Gastroenterology & hepatology

Auteurs

Membres identifiés du Cancéropôle Est :
Pr PEYRIN-BIROULET Laurent


Tous les auteurs :
Ma C, Khanna R, Maguire BR, Zou G, Bressler B, Hindryckx P, Mosli M, Sparrow MP, Hart AL, Leong RW, Rubin DT, Rémillard J, Shackelton LM, D'Haens GR, Danese S, Peyrin-Biroulet L, Sands BE, Panaccione R, Feagan BG, Jairath V

Résumé

Endoscopy is essential for measuring luminal disease activity in Crohn's disease. Existing indices for evaluating endoscopic Crohn's disease activity are only modestly correlated with clinical disease activity, contain items with ambiguous definitions and poor interobserver reliability, and do not have validated thresholds for defining clinically relevant changes. To address these issues, we conducted a multiphase study to develop and validate a novel endoscopic index for Crohn's disease.

Référence

Lancet Gastroenterol Hepatol. 2025 06 9;: