Naproxen and prednisolone reduced intestinal alteration and permeability and bacterial translocation in rat adjuvant-induced arthritis.

Date publication

juin 2025

Journal

Inflammopharmacology

Auteurs

Membres identifiés du Cancéropôle Est :
Dr PAIS DE BARROS Jean-Paul

Tous les auteurs :
Hecquet S, Totoson P, Martin H, Saas P, Pais-de-Barros JP, Tournier M, Prati C, Wendling D, Demougeot C, Verhoeven F

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/40493287

Résumé

In patients with spondyloarthritis, intestinal permeability (IP) and bacterial translocation (BT) has been described as increased. Anti-inflammatory medications are known to induce deleterious intestinal changes in the general population, their effects in case of arthritis have been poorly studied.

Mots clés

Animal model, Anti-inflammatory drugs, Intestinal barrier, Intestinal permeability, Non-steroidal anti-inflammatory drugs, Spondyloarthritis

Référence

Inflammopharmacology. 2025 06 10;: