The Impact of KRAS Status on Long-Term Outcomes After Thermal Ablation and Hepatic Resection for Liver-Only Colorectal Metastases: A New Clue for Tailoring Surgical Strategy on Tumor Biology?

Fiche publication

Date publication

mai 2025

Journal

World journal of surgery

Auteurs

Membres identifiés du Cancéropôle Est :
Pr PESSAUX Patrick

Tous les auteurs :
Giannone F, Sangiuolo F, Cassese G, Palucci M, Del Basso C, Lapergola A, Badessi G, Kianmanesh R, Pessaux P, Rhaiem R, Panaro F

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/40344254

Résumé

KRAS mutation is a negative prognostic factor for colorectal liver metastases (CRLM). Thermal ablation (TA) is considered a valid alternative to liver resection (LR) for CRLM in selected cases. This study aims to investigate the influence of KRAS status on long-term outcomes of TA during LR.