Fiche publication


Date publication

mai 2025

Journal

Inflammatory bowel diseases

Auteurs

Membres identifiés du Cancéropôle Est :
Pr PEYRIN-BIROULET Laurent


Tous les auteurs :
Gordon M, Shaban N, Sinopoulou V, Vuyyuru S, Radford S, Magro F, Armuzzi A, Peyrin-Biroulet L, Jairath V, Moran G

Résumé

When designing clinical trials, interpreting trial outcomes for guideline development or sharing decisions with patients in clinical practice, the clinical outcomes used and the implicit choices on what constitutes a clinically significant finding can vary greatly. This can lead to diversity or even inequity in care offered to patients with inflammatory bowel disease (IBD). The GRADE approach to guideline development has proposed a process to address this prospectively to solve these issues, but this has never been used in IBD. We aimed to develop the first international consensus set of outcome thresholds to establish their use in Crohn's disease and ulcerative colitis.

Mots clés

Crohn’s disease, IBD, Inflammatory Bowel Disease, Ulcerative colitis, clinical remission, endoscopic remission

Référence

Inflamm Bowel Dis. 2025 05 13;: