Fiche publication
Date publication
mai 2025
Journal
Annals of oncology : official journal of the European Society for Medical Oncology
Auteurs
Membres identifiés du Cancéropôle Est :
Dr RIOS Maria
,
Dr HERVIEU Alice
Tous les auteurs :
Blay JY, Devin Q, Toulmonde M, Dufresne A, Penel N, Adenis A, Rios M, Bertucci F, Duffaud F, Firmin N, Valentin T, Bompas E, Collard O, Pracht M, Hervieu A, Verret B, Ray-Coquard I, Cassier P, Henon C, Perol D, Italiano A, Chabaud S, Le Cesne A
Lien Pubmed
Résumé
Gastrointestinal stromal tumors (GIST) are driven in >75% of patients by mutations in KIT and PDGFRA kinases. Imatinib, a tyrosine kinase inhibitor, has shown efficacy in metastatic GIST but the long-term survival impact remains less understood, especially after extended treatment durations.
Mots clés
GIST, imatinib, long term, metastasis, survival
Référence
Ann Oncol. 2025 05 28;:
