Celastrol Improves Preference for a Fatty Acid, and Taste Bud and Systemic Inflammation in Diet-Induced Obese Mice.

Fiche publication

Date publication

avril 2025

Journal

Nutrients

Auteurs

Membres identifiés du Cancéropôle Est :
Dr HICHAMI Aziz

Tous les auteurs :
Benmouna M, Benammar C, Khan AS, Djeziri FZ, Hichami A, Khan NA

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/40284173

Résumé

Obesity is associated with the altered gustatory perception of dietary fatty acids. Celastrol, a triterpene, has been demonstrated to exert anti-obesity effects in rodents. We assessed the role of Celastrol in the modulation of the oro-sensory perception of lipids in control and high-fat diet (HFD)-induced obese mice.