Fiche publication


Date publication

mars 2025

Journal

Clinical nuclear medicine

Auteurs

Membres identifiés du Cancéropôle Est :
Pr NAMER Izzie-Jacques , Dr BUND Caroline


Tous les auteurs :
Todeschi J, Dannhoff G, Chammas A, Namer IJ, Bund C

Résumé

We report the case of a 6-year-old girl with Moyamoya disease and Alagille syndrome (JAGGED1 mutation). She presented left hemiparesis and central left facial paralysis due to an ischemic stroke in the right middle cerebral artery territory. Basal/acetazolamide stress brain perfusion SPECT showed decreased cerebral perfusion and cerebrovascular reserve in all the carotid artery territory, which can be improved by indirect bypass surgery. Ten months after surgery, the child no longer had a stroke, general condition has improved significantly, as has her school performance. Control SPECT showed successful revascularization visualized by significant improvement in cerebral perfusion and cerebrovascular reserve.

Référence

Clin Nucl Med. 2025 03 31;: