Fiche publication
Date publication
mars 2025
Journal
International journal of nanomedicine
Auteurs
Membres identifiés du Cancéropôle Est :
Dr PIETREMENT Olivier
Tous les auteurs :
Adame Brooks D, Piétrement O, Dardillac E, Castro Smirnov FA, Aranda P, Ruiz-Hitzky E, Lopez BS
Lien Pubmed
Résumé
Sepiolite nanofibers, which are natural silicates belonging to the clay mineral family, could be promising potential nanocarriers for the nonviral transfer of biomolecules. The physicochemical characteristics of sepiolite make it capable of binding various types of biological molecules, including polysaccharides, lipids, proteins and viruses. Sepiolite nanofibers have also been shown to bind effectively to various types of DNA molecules through electrostatic interactions, hydrogen bonds, cationic bridges and van der Waals forces. In this study, we analyzed the adsorption of DNA and proteins to sepiolite by analyzing the competition among these biomolecules during the adsorption process.
Mots clés
bionanomaterials, sepiolite clay mineral, sepiolite-DNA interaction, sepiolite-protein interaction
Référence
Int J Nanomedicine. 2025 03 5;20:2711-2726
