Fiche publication
Date publication
février 2020
Journal
BMJ open diabetes research & care
Auteurs
Membres identifiés du Cancéropôle Est :
Dr BENANI Alexandre
Tous les auteurs :
El-Mehdi M, Takhlidjt S, Khiar F, Prévost G, do Rego JL, do Rego JC, Benani A, Nedelec E, Godefroy D, Arabo A, Lefranc B, Leprince J, Anouar Y, Chartrel N, Picot M
Lien Pubmed
Résumé
26RFa (pyroglutamyl RFamide peptide (QRFP)) is a biologically active peptide that has been found to control feeding behavior by stimulating food intake, and to regulate glucose homeostasis by acting as an incretin. The aim of the present study was thus to investigate the impact of 26RFa gene knockout on the regulation of energy and glucose metabolism.
Mots clés
glucose-insulin homeostasis, incretin, insulin secretion, islet beta cell
Référence
BMJ Open Diabetes Res Care. 2020 02;8(1):