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Date publication

février 2020

Journal

BMJ open diabetes research & care

Auteurs

Membres identifiés du Cancéropôle Est :
Dr BENANI Alexandre


Tous les auteurs :
El-Mehdi M, Takhlidjt S, Khiar F, Prévost G, do Rego JL, do Rego JC, Benani A, Nedelec E, Godefroy D, Arabo A, Lefranc B, Leprince J, Anouar Y, Chartrel N, Picot M

Résumé

26RFa (pyroglutamyl RFamide peptide (QRFP)) is a biologically active peptide that has been found to control feeding behavior by stimulating food intake, and to regulate glucose homeostasis by acting as an incretin. The aim of the present study was thus to investigate the impact of 26RFa gene knockout on the regulation of energy and glucose metabolism.

Mots clés

glucose-insulin homeostasis, incretin, insulin secretion, islet beta cell

Référence

BMJ Open Diabetes Res Care. 2020 02;8(1):