Fiche publication
Date publication
juin 2021
Journal
International journal of obesity (2005)
Auteurs
Membres identifiés du Cancéropôle Est :
Dr BENANI Alexandre
Tous les auteurs :
Fouesnard M, Zoppi J, Petera M, Le Gleau L, Migné C, Devime F, Durand S, Benani A, Chaffron S, Douard V, Boudry G
Lien Pubmed
Résumé
Early hyperphagia and hypothalamic inflammation encountered after Western diet (WD) are linked to rodent propensity to obesity. Inflammation in several brain structures has been associated with gut dysbiosis. Since gut microbiota is highly sensitive to dietary changes, we hypothesised that immediate gut microbiota adaptation to WD in rats is involved in inflammation-related hypothalamic modifications.
Mots clés
Animals, Brain-Gut Axis, physiology, Cytokines, metabolism, Diet, Western, adverse effects, Dysbiosis, metabolism, Gastrointestinal Microbiome, physiology, Hypothalamus, metabolism, Inflammation, metabolism, Male, Rats, Rats, Wistar
Référence
Int J Obes (Lond). 2021 06;45(6):1271-1283
