Fiche publication
Date publication
février 2025
Journal
Computers in biology and medicine
Auteurs
Membres identifiés du Cancéropôle Est :
Pr BARBERI-HEYOB Muriel
,
Dr THOMAS Noémie
,
Dr RETIF Paul
,
Dr DAOUK Joël
Tous les auteurs :
Blind S, Lerouge L, Gries M, Retif P, Thomas N, Barberi-Heyob M, Daouk J
Lien Pubmed
Résumé
The use of numerical models to predict radiosensitizing properties induced by metal-based nanoparticles (NPs) remains a real challenge in oncology. As most of the interactions due to radiation in biological environments originate from the secondary particles produced, we aim to formalize the relationship between these secondary particles, the irradiation dose and the NP concentration, to optimize mathematical and numerical tools for assessing NP-induced radiosensitization.
Mots clés
In vitro experiments, Monte Carlo simulations, Radiophysical prediction, Radiosensitizing potential of nanoparticles
Référence
Comput Biol Med. 2025 02 18;188:109861
