Fiche publication
Date publication
février 2015
Journal
Biological psychiatry
Auteurs
Membres identifiés du Cancéropôle Est :
Dr YALCIN CHRISTMANN Ipek
,
Dr BARROT Michel
Tous les auteurs :
Barthas F, Sellmeijer J, Hugel S, Waltisperger E, Barrot M, Yalcin I
Lien Pubmed
Résumé
Besides chronic stress, chronic pain is a prevalent determinant for depression. Changes induced in specific brain regions by sustained pain may alter the processing of affective information, thus resulting in anxiodepressive disorders. Here, we compared the role of the anterior cingulate cortex (ACC) and the posterior insular cortex in the anxiodepressive, sensory, and affective aspects of chronic pain.
Mots clés
Anterior cingulate cortex, Anxiety, Behavior, Depression, Insular cortex, Neuropathic pain, Optogenetics
Référence
Biol Psychiatry. 2015 02 1;77(3):236-245