Fiche publication


Date publication

février 2015

Journal

Biological psychiatry

Auteurs

Membres identifiés du Cancéropôle Est :
Dr YALCIN CHRISTMANN Ipek , Dr BARROT Michel


Tous les auteurs :
Barthas F, Sellmeijer J, Hugel S, Waltisperger E, Barrot M, Yalcin I

Résumé

Besides chronic stress, chronic pain is a prevalent determinant for depression. Changes induced in specific brain regions by sustained pain may alter the processing of affective information, thus resulting in anxiodepressive disorders. Here, we compared the role of the anterior cingulate cortex (ACC) and the posterior insular cortex in the anxiodepressive, sensory, and affective aspects of chronic pain.

Mots clés

Anterior cingulate cortex, Anxiety, Behavior, Depression, Insular cortex, Neuropathic pain, Optogenetics

Référence

Biol Psychiatry. 2015 02 1;77(3):236-245