Fiche personne
Coordonnées
ICube UMR 7357
Centre de recherche en biomédecine de Strasbourg
1 rue Eugène Boeckel
67084 STRASBOURG Cedex
03 68 85 32 96
Territoire
Alsace
Statut
Enseignant-Chercheur
Affiliation
Université de Strasbourg (Unistra)
iCube UMR 7357 - Laboratoire des sciences de l'ingénieur, de l'informatique et de l'imagerie (iCube)
Équipes/plateformes
Publications
The extraordinary satellitome diversity of freshwater crayfish: a driver of genome evolution.
Bonassin L, Boštjančić LL, Rutz C, Francesconi C, Schardt L, Baranski D, Greve C, Pârvulescu L, Besendorfer V, Mlinarec J, Maguire I, Theissinger K, Lecompte O
Mob DNA. 2026 04 28;17(1):
Profylo: A Python Package for Phylogenetic Profile Comparison and Analysis.
Schoenstein M, Mermillod P, Kress A, Lecompte O, Nevers Y
J Mol Evol. 2025 12;93(6):806-819
Characterisation of the noble crayfish immune response to oomycete-derived immunostimulants.
Tarandek A, Boštjančić LL, Francesconi C, Bonassin L, Schardt L, Jussila J, Kokko H, Schwenk K, Hudina S, Lecompte O, Theissinger K
Fish Shellfish Immunol. 2025 11;166:110666
Expression of C/EBP and Kr-h1 transcription factors under immune stimulation in the noble crayfish.
Boštjančić LL, Dragičević P, Bonassin L, Francesconi C, Tarandek A, Schardt L, Rutz C, Hudina S, Schwenk K, Lecompte O, Theissinger K
Gene. 2024 12 15;929:148813
New developments for the Quest for Orthologs benchmark service.
Altenhoff A, Nevers Y, Tran V, Jyothi D, Martin M, Cosentino S, Majidian S, Marcet-Houben M, Fuentes-Palacios D, Persson E, Walsh T, Lecompte O, Gabaldón T, Kelly S, Hu Y, Iwasaki W, Capella-Gutierrez S, Dessimoz C, Thomas PD, Ebersberger I, Sonnhammer E
NAR Genom Bioinform. 2024 12;6(4):lqae167
High variation of virulence in Aphanomyces astaci strains lacks association with pathogenic traits and mtDNA haplogroups.
Francesconi C, Boštjančić LL, Bonassin L, Schardt L, Rutz C, Makkonen J, Schwenk K, Lecompte O, Theissinger K
J Invertebr Pathol. 2024 09;206:108153
Genomic insights into the conservation status of the Idle Crayfish Austropotamobius bihariensis Pârvulescu, 2019: low genetic diversity in the endemic crayfish species of the Apuseni Mountains.
Bonassin L, Pârvulescu L, Boštjančić LL, Francesconi C, Paetsch J, Rutz C, Lecompte O, Theissinger K
BMC Ecol Evol. 2024 06 11;24(1):78
The MetaInvert soil invertebrate genome resource provides insights into below-ground biodiversity and evolution.
Collins G, Schneider C, Boštjančić LL, Burkhardt U, Christian A, Decker P, Ebersberger I, Hohberg K, Lecompte O, Merges D, Muelbaier H, Romahn J, Römbke J, Rutz C, Schmelz R, Schmidt A, Theissinger K, Veres R, Lehmitz R, Pfenninger M, Bálint M
Commun Biol. 2023 12 8;6(1):1241
Temporal dynamics of the immune response in Astacus astacus (Linnaeus, 1758) challenged with Aphanomyces astaci Schikora, 1906.
Boštjančić LL, Francesconi C, Bonassin L, Hudina S, Gračan R, Maguire I, Rutz C, Beck A, Dobrović A, Lecompte O, Theissinger K
Fish Shellfish Immunol. 2023 10 28;:109185
Abundance and Diversification of Repetitive Elements in Decapoda Genomes.
Rutz C, Bonassin L, Kress A, Francesconi C, Boštjančić LL, Merlat D, Theissinger K, Lecompte O
Genes (Basel). 2023 08 15;14(8):
Protein length distribution is remarkably uniform across the tree of life.
Nevers Y, Glover NM, Dessimoz C, Lecompte O
Genome Biol. 2023 06 8;24(1):135
Real or fake? Measuring the impact of protein annotation errors on estimates of domain gain and loss events.
Kress A, Poch O, Lecompte O, Thompson JD
Front Bioinform. 2023 04 20;3:1178926
Dataset of the de novo assembly and annotation of the marbled crayfish and the noble crayfish hepatopancreas transcriptomes.
Boštjančić LL, Francesconi C, Rutz C, Hoffbeck L, Poidevin L, Kress A, Jussila J, Makkonen J, Feldmeyer B, Bálint M, Schwenk K, Lecompte O, Theissinger K
BMC Res Notes. 2022 08 22;15(1):281
Host-pathogen coevolution drives innate immune response to Aphanomyces astaci infection in freshwater crayfish: transcriptomic evidence.
Boštjančić LL, Francesconi C, Rutz C, Hoffbeck L, Poidevin L, Kress A, Jussila J, Makkonen J, Feldmeyer B, Bálint M, Schwenk K, Lecompte O, Theissinger K
BMC Genomics. 2022 08 22;23(1):600
The Quest for Orthologs orthology benchmark service in 2022.
Nevers Y, Jones TEM, Jyothi D, Yates B, Ferret M, Portell-Silva L, Codo L, Cosentino S, Marcet-Houben M, Vlasova A, Poidevin L, Kress A, Hickman M, Persson E, Piližota I, Guijarro-Clarke C, ,Iwasaki W, Lecompte O, Sonnhammer E, Roos DS, Gabaldón T, Thybert D, Thomas PD, Hu Y, Emms DM, Bruford E, Capella-Gutierrez S, Martin MJ, Dessimoz C, Altenhoff A
Nucleic Acids Res. 2022 07 5;50(W1):W623-W632
Novel Approach Combining Transcriptional and Evolutionary Signatures to Identify New Multiciliation Genes.
Defosset A, Merlat D, Poidevin L, Nevers Y, Kress A, Poch O, Lecompte O
Genes (Basel). 2021 Sep 21;12(9):
Ten Years of Collaborative Progress in the Quest for Orthologs.
Linard B, Ebersberger I, McGlynn SE, Glover N, Mochizuki T, Patricio M, Lecompte O, Nevers Y, Thomas PD, Gabaldón T, Sonnhammer E, Dessimoz C, Uchiyama I,
Mol Biol Evol. 2021 07 29;38(8):3033-3045
Proteome-scale detection of differential conservation patterns at protein and sub-protein levels with BLUR.
Defosset A, Kress A, Nevers Y, Ripp R, Thompson JD, Poch O, Lecompte O
Genome Biol Evol. 2020 Nov 19;:
The Quest for Orthologs benchmark service and consensus calls in 2020.
Altenhoff AM, Garrayo-Ventas J, Cosentino S, Emms D, Glover NM, Hernández-Plaza A, Nevers Y, Sundesha V, Szklarczyk D, Fernández JM, Codó L, For Orthologs Consortium TQ, Gelpi JL, Huerta-Cepas J, Iwasaki W, Kelly S, Lecompte O, Muffato M, Martin MJ, Capella-Gutierrez S, Thomas PD, Sonnhammer E, Dessimoz C
Nucleic Acids Res. 2020 07 2;48(W1):W538-W545
OrthoInspector 3.0: open portal for comparative genomics.
Nevers Y, Kress A, Defosset A, Ripp R, Linard B, Thompson JD, Poch O, Lecompte O
Nucleic Acids Res.. 2018 Oct 31;:
PROBE: analysis and visualization of protein block-level evolution.
Kress A, Lecompte O, Poch O, Thompson JD
Bioinformatics. 2018 May 7;:
MyGeneFriends: A Social Network Linking Genes, Genetic Diseases, and Researchers.
Allot A, Chennen K, Nevers Y, Poidevin L, Kress A, Ripp R, Thompson JD, Poch O, Lecompte O
J. Med. Internet Res.. 2017 Jun;19(6):e212
Insights into ciliary genes and evolution from multi-level phylogenetic profiling.
Nevers Y, Prasad MK, Poidevin L, Chennen K, Allot A, Kress A, Ripp R, Thompson JD, Dollfus H, Poch O, Lecompte O
Mol. Biol. Evol.. 2017 Apr;:
Proteome Evolution of Deep-Sea Hydrothermal Vent Alvinellid Polychaetes Supports the Ancestry of Thermophily and Subsequent Adaptation to Cold in Some Lineages.
Fontanillas E, Galzitskaya OV, Lecompte O, Lobanov MY, Tanguy A, Mary J, Girguis PR, Hourdez S, Jollivet D
Genome Biol Evol. 2017 02 1;9(2):279-296
Standardized benchmarking in the quest for orthologs.
Altenhoff AM, Boeckmann B, Capella-Gutierrez S, Dalquen DA, DeLuca T, Forslund K, Huerta-Cepas J, Linard B, Pereira C, Pryszcz LP, Schreiber F, da Silva AS, Szklarczyk D, Train CM, Bork P, Lecompte O, von Mering C, Xenarios I, Sjölander K, Jensen LJ, Martin MJ, Muffato M, ,Gabaldón T, Lewis SE, Thomas PD, Sonnhammer E, Dessimoz C
Nat Methods. 2016 05;13(5):425-30
OrthoInspector 2.0: Software and database updates.
Linard B, Allot A, Schneider R, Morel C, Ripp R, Bigler M, Thompson JD, Poch O, Lecompte O
Bioinformatics. 2015 Feb 1;31(3):447-8
Tex19 and Sectm1 concordant molecular phylogenies support co-evolution of both eutherian-specific genes.
Bianchetti L, Tarabay Y, Lecompte O, Stote R, Poch O, Dejaegere A, Viville S
BMC Evol Biol. 2015 Oct 12;15:222
Retinoic acid receptor subtype-specific transcriptotypes in the early zebrafish embryo.
Samarut E, Gaudin C, Hughes S, Gillet B, de Bernard S, Jouve PE, Buffat L, Allot A, Lecompte O, Berekelya L, Rochette-Egly C, Laudet V
Mol Endocrinol. 2014 Feb;28(2):260-72
PARSEC: PAtteRn SEarch and Contextualization.
Allot A, Anno YN, Poidevin L, Ripp R, Poch O, Lecompte O
Bioinformatics. 2013 Oct 15;29(20):2643-4
Detection and characterisation of mutations responsible for allele-specific protein thermostabilities at the Mn-superoxide dismutase gene in the deep-sea hydrothermal vent polychaete Alvinella pompejana.
Bruneaux M, Mary J, Verheye M, Lecompte O, Poch O, Jollivet D, Tanguy A
J Mol Evol. 2013 May;76(5):295-310
Functional insights into the core-TFIIH from a comparative survey.
Bedez F, Linard B, Brochet X, Ripp R, Thompson JD, Moras D, Lecompte O, Poch O
Genomics. 2013 Mar;101(3):178-86
Whole-exome sequencing identifies LRIT3 mutations as a cause of autosomal-recessive complete congenital stationary night blindness.
Zeitz C, Jacobson SG, Hamel CP, Bujakowska K, Neuille M, Orhan E, Zanlonghi X, Lancelot ME, Michiels C, Schwartz SB, Bocquet B, Antonio A, Audier C, Letexier M, Saraiva JP, Luu TD, Sennlaub F, Nguyen H, Poch O, Dollfus H, Lecompte O, Kohl S, Sahel JA, Bhattacharya SS, Audo I
Am J Hum Genet. 2013 Jan 10;92(1):67-75
Whole-exome sequencing identifies mutations in GPR179 leading to autosomal-recessive complete congenital stationary night blindness.
Audo I, Bujakowska K, Orhan E, Poloschek CM, Defoort-Dhellemmes S, Drumare I, Kohl S, Luu TD, Lecompte O, Zrenner E, Lancelot ME, Antonio A, Germain A, Michiels C, Audier C, Letexier M, Saraiva JP, Leroy BP, Munier FL, Mohand-Said S, Lorenz B, Friedburg C, Preising M, Kellner U, Renner AB, Moskova-Doumanova V, Berger W, Wissinger B, Hamel CP, Schorderet DF, De Baere E, Sharon D, Banin E, Jacobson SG, Bonneau D, Zanlonghi X, Le Meur G, Casteels I, Koenekoop R, Long VW, Meire F, Prescott K, de Ravel T, Simmons I, Nguyen H, Dollfus H, Poch O, Leveillard T, Nguyen-Ba-Charvet K, Sahel JA, Bhattacharya SS, Zeitz C
Am J Hum Genet. 2012 Feb 10;90(2):321-30.
Evolutionary analysis of the ENTH/ANTH/VHS protein superfamily reveals a coevolution between membrane trafficking and metabolism.
De Craene JO, Ripp R, Lecompte O, Thompson JD, Poch O, Friant S
BMC Genomics. 2012 Jul 2;13:297
Proteome adaptation to high temperatures in the ectothermic hydrothermal vent Pompeii worm.
Jollivet D, Mary J, Gagniere N, Tanguy A, Fontanillas E, Boutet I, Hourdez S, Segurens B, Weissenbach J, Poch O, Lecompte O
PLoS One. 2012;7(2):e31150
Genome-wide in silico identification of new conserved and functional retinoic acid receptor response elements (direct repeats separated by 5 bp).
Lalevee S, Anno YN, Chatagnon A, Samarut E, Poch O, Laudet V, Benoit G, Lecompte O, Rochette-Egly C
J Biol Chem. 2011 Sep 23;286(38):33322-34
Genome-wide evidence for an essential role of the human Staf/ZNF143 transcription factor in bidirectional transcription.
Anno YN, Myslinski E, Ngondo-Mbongo RP, Krol A, Poch O, Lecompte O, Carbon P
Nucleic Acids Res. 2011 Apr;39(8):3116-27
A comprehensive benchmark study of multiple sequence alignment methods: current challenges and future perspectives.
Thompson JD, Linard B, Lecompte O, Poch O
PLoS One. 2011 Mar 31;6(3):e18093.
OrthoInspector: comprehensive orthology analysis and visual exploration.
Linard B, Thompson JD, Poch O, Lecompte O
BMC Bioinformatics. 2011 Jan 10;12:11.
SM2PH-db: an interactive system for the integrated analysis of phenotypic consequences of missense mutations in proteins involved in human genetic diseases.
Friedrich A, Garnier N, Gagniere N, Nguyen H, Albou LP, Biancalana V, Bettler E, Deleage G, Lecompte O, Muller J, Moras D, Mandel JL, Toursel T, Moulinier L, Poch O
Hum Mutat. 2010 Feb;31(2):127-35.
Insights into metazoan evolution from Alvinella pompejana cDNAs.
Gagniere N, Jollivet D, Boutet I, Brelivet Y, Busso D, Da Silva C, Gaill F, Higuet D, Hourdez S, Knoops B, Lallier F, Leize-Wagner E, Mary J, Moras D, Perrodou E, Rees JF, Segurens B, Shillito B, Tanguy A, Thierry JC, Weissenbach J, Wincker P, Zal F, Poch O, Lecompte O
BMC Genomics. 2010 Nov 16;11:634.
Ortho-proteogenomics: multiple proteomes investigation through orthology and a new MS-based protocol.
Gallien S, Perrodou E, Carapito C, Deshayes C, Reyrat JM, Van Dorsselaer A, Poch O, Schaeffer C, Lecompte O
Genome Res. 2009 Jan;19(1):128-35
PtdIns5P regulation through evolution: roles in membrane trafficking?
Lecompte O, Poch O, Laporte J
Trends Biochem Sci. 2008 Oct;33(10):453-60
Interrupted coding sequences in Mycobacterium smegmatis: authentic mutations or sequencing errors?
Deshayes C, Perrodou E, Gallien S, Euphrasie D, Schaeffer C, Van-Dorsselaer A, Poch O, Lecompte O, Reyrat JM
Genome Biol. 2007;8(2):R20.
ICDS database: interrupted CoDing sequences in prokaryotic genomes.
Perrodou E, Deshayes C, Muller J, Schaeffer C, Van Dorsselaer A, Ripp R, Poch O, Reyrat JM, Lecompte O
Nucleic Acids Res. 2006 Jan 1;34(Database issue):D338-43.
Cloning, purification and crystallization of a Walker-type Pyrococcus abyssi ATPase family member.
Uhring M, Bey G, Lecompte O, Cavarelli J, Moras D, Poch O
Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 Oct 1;61(Pt
vALId: validation of protein sequence quality based on multiple alignment data.
Bianchetti L, Thompson JD, Lecompte O, Plewniak F, Poch O
J Bioinform Comput Biol. 2005 Aug;3(4):929-47.