Dr VEJUX Anne

7-ketocholesterol as a theranostic target: potential applications and future perspectives.

Lizard G, Sassi K, Mackrill JJ, Ghzaiel I, Meziane S, Hassen E, Abdelkarim M, Masmoudi-Kouki O, Ghrairi T, Brahmi F, Gargouri A, Rezig L, Benkalifa R, Khallouki F, El Midaoui A, Pincemail J, Atanasov AG, Vejux A, Millot N

Chem Phys Lipids. 2026 04 3;:105588

Oxysterol-Induced Inflammation in Human Diseases: Strategies for Treatment with Natural Compounds and Synthetic Molecules.

Brahmi F, Mackrill JJ, Ghzaiel I, Rezig L, Benkhalifa R, Zarrouk A, Jouanny P, Vejux A, Lizard G

Molecules. 2025 07 7;30(13):

Oxysterols, age-related-diseases and nutritherapy: focus on 7-ketocholesterol and 7β-hydroxycholesterol.

Vejux A, Ghzaiel I, Mackrill JJ, Dias IHK, Rezig L, Ksila M, Zarrouk A, Nury T, Brahmi F, El Midaoui A, Meziane S, Atanasov AG, Hammami S, Latruffe N, Jouanny P, Lizard G

Prostaglandins Other Lipid Mediat. 2025 04 9;:106993

Arginase Activity Inhibition With Thymoquinone Induces a Hybrid Type of Cell-Death in MDA-MB-231 Cell Line.

Bday J, Souid M, Pires V, Gabbouj S, Véjux A, Lizard G, Hassen E

J Biochem Mol Toxicol. 2025 02;39(2):e70130

Maternal Diet and Vulnerability to Cognitive Impairment in Adulthood: Possible Link with Alzheimer's Disease?

Merle L, Rastelli M, Datiche F, Véjux A, Jacquin-Piques A, Bouret SG, Benani A

Neuroendocrinology. 2025 01 10;:1-24

Octadecaneuropeptide, ODN, Promotes Cell Survival against 6-OHDA-Induced Oxidative Stress and Apoptosis by Modulating the Expression of miR-34b, miR-29a, and miR-21in Cultured Astrocytes.

Bourzam A, Hamdi Y, Bahdoudi S, Duraisamy K, El Mehdi M, Basille-Dugay M, Dlimi O, Kharrat M, Vejux A, Lizard G, Ghrairi T, Lefranc B, Vaudry D, Boutin JA, Leprince J, Masmoudi-Kouki O

Cells. 2024 07 12;13(14):

Characterization of Silybum marianum and Silybum eburneum seed oils: Phytochemical profiles and antioxidant properties supporting important nutritional interests.

Maaloul S, Ghzaiel I, Mahmoudi M, Mighri H, Pires V, Vejux A, Martine L, de Barros JP, Prost-Camus E, Boughalleb F, Lizard G, Abdellaoui R

PLoS One. 2024 06 14;19(6):e0304021

Exploring the Role of Apigenin in Neuroinflammation: Insights and Implications.

Charrière K, Schneider V, Perrignon-Sommet M, Lizard G, Benani A, Jacquin-Piques A, Vejux A

Int J Mol Sci. 2024 05 6;25(9):

Tunisian Species: Important Sources of Polyphenols, Organic Acids, Minerals, and Proteins across Various Plant Organs.

Maaloul S, Mahmoudi M, Mighri H, Ghzaiel I, Bouhamda T, Boughalleb F, El Midaoui A, Vejux A, Lizard G, Abdellaoui R

Plants (Basel). 2024 03 29;13(7):

Benefits of rutin on mitochondrial function and inflammation in an aluminum-induced neurotoxicity rat model: Potential interest for the prevention of neurodegeneration.

Kessas K, Lounis W, Chouari Z, Vejux A, Lizard G, Kharoubi O

Biochimie. 2024 02 24;:

Cytoprotective effects of α-linolenic acid, eicosapentaenoic acid, docosahexaenoic acid, oleic acid and α-tocopherol on 7-ketocholesterol - Induced oxiapoptophagy: Major roles of PI3-K / PDK-1 / Akt signaling pathway and glutathione peroxidase activity in

Yammine A, Ghzaiel I, Pires V, Zarrouk A, Kharoubi O, Greige-Gerges H, Auezova L, Lizard G, Vejux A

Curr Res Toxicol. 2024 02 8;6:100153

Microgliosis: a double-edged sword in the control of food intake.

Salvi J, Andreoletti P, Audinat E, Balland E, Ben Fradj S, Cherkaoui-Malki M, Heurtaux T, Liénard F, Nédélec E, Rovère C, Savary S, Véjux A, Trompier D, Benani A

FEBS J. 2024 02;291(4):615-631

Chemical and Biochemical Features of Spinasterol and Schottenol.

Khallouki F, Ksila M, Ghzaiel I, Essadek S, Joutey MT, Maaloul S, Zennouhi W, Benbacer L, Bourhia M, Hajji L, Zarrouk A, Rezig L, Rup-Jacques S, Abdellaoui R, Ghrairi T, Masmoudi-Kouki O, Nasser B, Andreoletti P, Mustapha-Cherkaoui-Malki,Samadi M, Vejux A, Lizard G

Adv Exp Med Biol. 2024 ;1440:45-55

Impact of Oxysterols in Age-Related Disorders and Strategies to Alleviate Adverse Effects.

Ghosh S, Ghzaiel I, Vejux A, Meaney S, Nag S, Lizard G, Tripathi G, Naez F, Paul S

Adv Exp Med Biol. 2024 ;1440:163-191

In Vitro Evaluation of the Effects of 7-Ketocholesterol and 7β-Hydroxycholesterol on the Peroxisomal Status: Prevention of Peroxisomal Damages and Concept of Pexotherapy.

Ghzaiel I, Maaloul S, Ksila M, Namsi A, Yammine A, Debbabi M, Badreddine A, Meddeb W, Pires V, Nury T, Ménétrier F, Avoscan L, Zarrouk A, Baarine M, Masmoudi-Kouki O, Ghrairi T, Abdellaoui R, Nasser B, Hammami S, Hammami M, Samadi M, Vejux A, Lizard G

Adv Exp Med Biol. 2024 ;1440:437-452

Therapeutic Applications of Oxysterols and Derivatives in Age-Related Diseases, Infectious and Inflammatory Diseases, and Cancers.

Ksila M, Ghzaiel I, Sassi K, Zarrouk A, Leoni V, Poli G, Rezig L, Pires V, Meziane S, Atanasov AG, Hammami S, Hammami M, Masmoudi-Kouki O, Hamdi O, Jouanny P, Samadi M, Vejux A, Ghrairi T, Lizard G

Adv Exp Med Biol. 2024 ;1440:379-400

Thymus atlanticus: A Source of Nutrients with Numerous Health Benefits and Important Therapeutic Potential for Age-Related Diseases.

El Midaoui A, Khallouki F, Couture R, Moldovan F, Ismael MA, Ongali B, Akoume MY, Alem C, Ait Boughrous A, Zennouhi W, Roqai MC, Hajji L, Ghzaiel I, Vejux A, Lizard G

Nutrients. 2023 09 21;15(18):

The Action Mechanisms, Anti-Cancer and Antibiotic-Modulation Potential of L. Extract.

Ginovyan M, Babayan A, Shirvanyan A, Minasyan A, Qocharyan M, Kusznierewicz B, Koss-Mikołajczyk I, Avtandilyan N, Vejux A, Bartoszek A, Sahakyan N

Discov Med. 2023 08;35(177):590-611

Cell Death and Neurodegenerative Diseases: Mechanisms and Cytoprotective Molecules.

Vejux A

Int J Mol Sci. 2023 07 14;24(14):

Effects of polyphenols and their metabolites on age-related diseases.

Zhor C, Wafaa L, Ghzaiel I, Kessas K, Zarrouk A, Ksila M, Ghrairi T, Latruffe N, Masmoudi-Kouki O, El Midaoui A, Vervandier-Fasseur D, Hammami M, Lizard G, Vejux A, Kharoubi O

Biochem Pharmacol. 2023 07 4;214:115674

Neurodegeneration, oxidative stress and lipid metabolism plasma biomarkers to differentiate Parkinson's disease from atypical parkinsonian syndromes.

Schneider V, Vejux A, Nury T, Dupont G, Pais de Barros JP, Lakomy D, Lizard G, Moreau T

Rev Neurol (Paris). 2023 06 14;:

7β-hydroxycholesterol and 7-ketocholesterol: new oxidative stress biomarkers of sarcopenia inducing cytotoxic effects on myoblasts and myotubes.

Ghzaiel I, Zarrouk A, Pires V, de Barros JP, Hammami S, Ksila M, Hammami M, Ghrairi T, Jouanny P, Vejux A, Lizard G

J Steroid Biochem Mol Biol. 2023 06 5;:106345

Characterization of Cell Death Induced by Imine Analogs of Trans-Resveratrol: Induction of Mitochondrial Dysfunction and Overproduction of Reactive Oxygen Species Leading to, or Not, Apoptosis without the Increase in the S-Phase of the Cell Cycle.

Ksila M, Ghzaiel I, Pires V, Ghrairi T, Masmoudi-Kouki O, Latruffe N, Vervandier-Fasseur D, Vejux A, Lizard G

Molecules. 2023 04 3;28(7):

The Role of Oxidative Stress-Mediated Inflammation in the Development of T2DM-Induced Diabetic Nephropathy: Possible Preventive Action of Tannins and Other Oligomeric Polyphenols.

Sahakyan G, Vejux A, Sahakyan N

Molecules. 2022 12 18;27(24):

Oxiapoptophagy in Age-Related Diseases. Comment on Ouyang et al. 7-Ketocholesterol Induces Oxiapoptophagy and Inhibits Osteogenic Differentiation in MC3T3-E1 Cells. 2022, , 2882.

Ghzaiel I, Nury T, Zarrouk A, Vejux A, Lizard G

Cells. 2022 11 15;11(22):

Cytoprotective activities of representative nutrients from the Mediterranean diet and of Mediterranean oils against 7-ketocholesterol- and 7β-hydroxycholesterol-induced cytotoxicity: application to age-related diseases and civilization diseases.

Rezig L, Ghzaiel I, Ksila M, Yammine A, Nury T, Zarrouk A, Samadi M, Chouaibi M, Vejux A, Lizard G

Steroids. 2022 08 24;:109093

Cytotoxic and Antioxidant Activities of Imine Analogs of Trans-Resveratrol towards Murine Neuronal N2a Cells.

Ksila M, Vejux A, Prost-Camus E, Durand P, Ghzaiel I, Nury T, Duprey D, Meziane S, Masmoudi-Kouki O, Latruffe N, Ghrairi T, Prost M, Lizard G, Vervandier-Fasseur D

Molecules. 2022 07 23;27(15):

Role of Diet and Nutrients in SARS-CoV-2 Infection: Incidence on Oxidative Stress, Inflammatory Status and Viral Production.

Brahmi F, Vejux A, Ghzaiel I, Ksila M, Zarrouk A, Ghrairi T, Essadek S, Mandard S, Leoni V, Poli G, Vervandier-Fasseur D, Kharoubi O, El Midaoui A, Atanasov AG, Meziane S, Latruffe N, Nasser B, Bouhaouala-Zahar B, Masmoudi-Kouki O, Madani K, Boulekbache-Makhlouf L, Lizard G

Nutrients. 2022 05 25;14(11):

Protective effects of milk thistle (Sylibum marianum) seed oil and α-tocopherol against 7β-hydroxycholesterol-induced peroxisomal alterations in murine C2C12 myoblasts: nutritional insights associated with the concept of pexotherapy.

Ghzaiel I, Zarrouk A, Essadek S, Martine L, Hammouda S, Yammine A, Ksila M, Nury T, Meddeb W, Tahri Joutey M, Mihoubi W, Caccia C, Leoni V, Samadi M, Acar N, Andreoletti P, Hammami S, Ghrairi T, Vejux A, Hammami M, Lizard G

Steroids. 2022 Apr 2;:109032

Saffron ( L.): A Source of Nutrients for Health and for the Treatment of Neuropsychiatric and Age-Related Diseases.

El Midaoui A, Ghzaiel I, Vervandier-Fasseur D, Ksila M, Zarrouk A, Nury T, Khallouki F, El Hessni A, Ibrahimi SO, Latruffe N, Couture R, Kharoubi O, Brahmi F, Hammami S, Masmoudi-Kouki O, Hammami M, Ghrairi T, Vejux A, Lizard G

Nutrients. 2022 Jan 29;14(3):

Profiles of Fatty Acids, Polyphenols, Sterols, and Tocopherols and Scavenging Property of Mediterranean Oils: New Sources of Dietary Nutrients for the Prevention of Age-related Diseases.

Rezig L, Martine L, Nury T, Msaada K, Mahfoudhi N, Ghzaiel I, Prost-Camus E, Durand P, Midaoui AE, Acar N, Latruffe N, Vejux A, Lizard G

J Oleo Sci. 2022 ;71(8):1117-1133

Cell Death, Inflammation and Oxidative Stress in Neurodegenerative Diseases: Mechanisms and Cytoprotective Molecules.

Vejux A

Int J Mol Sci. 2021 12 20;22(24):

Antioxidant Properties and Cytoprotective Effect of L. Seed Oil against 7β-Hydroxycholesterol-Induced Toxicity in C2C12 Myoblasts: Reduction in Oxidative Stress, Mitochondrial and Peroxisomal Dysfunctions and Attenuation of Cell Death.

Ghzaiel I, Zarrouk A, Nury T, Libergoli M, Florio F, Hammouda S, Ménétrier F, Avoscan L, Yammine A, Samadi M, Latruffe N, Biressi S, Levy D, Bydlowski SP, Hammami S, Vejux A, Hammami M, Lizard G

Antioxidants (Basel). 2021 Nov 5;10(11):

Involvement of Microglia in Neurodegenerative Diseases: Beneficial Effects of Docosahexahenoic Acid (DHA) Supplied by Food or Combined with Nanoparticles.

Charrière K, Ghzaiel I, Lizard G, Vejux A

Int J Mol Sci. 2021 Sep 30;22(19):

7-ketocholesterol: effects on viral infections and hypothetical contribution in COVID-19.

Ghzaiel I, Sassi K, Zarrouk A, Nury T, Ksila M, Leoni V, Bouhaouala-Zahar B, Hammami S, Hammami M, Mackrill JJ, Samadi M, Ghrairi T, Vejux A, Lizard G

J Steroid Biochem Mol Biol. 2021 Jun 9;:105939

Essential Oils, and , Chemosensitize Resistant Human Uterine Sarcoma MES-SA/Dx5 Cells to Doxorubicin by Inducing Apoptosis and Targeting P-Glycoprotein.

Lahmar A, Mathey A, Aires V, Elgueder D, Vejux A, Khlifi R, Sioud F, Chekir-Ghedira L, Delmas D

Nutrients. 2021 May 19;13(5):

Attenuation of 7-ketocholesterol- and 7β-hydroxycholesterol-induced oxiapoptophagy by nutrients, synthetic molecules and oils: potential for the prevention of age-related diseases.

Nury T, Yammine A, Ghzaiel I, Sassi K, Zarrouk A, Brahmi F, Samadi M, Rup-Jacques S, Vervandier-Fasseur D, Pais de Barros JP, Bergas V, Ghosh S, Majeed M, Pande A, Atanasov A, Hammami S, Hammami M, Mackrill J, Nasser B, Andreoletti P, Cherkaoui-Malki M, Vejux A, Lizard G

Ageing Res Rev. 2021 Mar 24;:101324

Oxysterols and Multiple Sclerosis: physiopathology, evolutive biomarkers and therapeutic strategy.

Vejux A, Ghzaiel I, Nury T, Schneider V, Charrière K, Sghaier R, Zarrouk A, Leoni V, Moreau T, Lizard G

J Steroid Biochem Mol Biol. 2021 Mar 5;:105870

Prevention by Dietary Polyphenols (Resveratrol, Quercetin, Apigenin) Against 7-Ketocholesterol-Induced Oxiapoptophagy in Neuronal N2a Cells: Potential Interest for the Treatment of Neurodegenerative and Age-Related Diseases.

Yammine A, Zarrouk A, Nury T, Vejux A, Latruffe N, Vervandier-Fasseur D, Samadi M, Mackrill JJ, Greige-Gerges H, Auezova L, Lizard G

Cells. 2020 Oct 23;9(11):

Oxiapoptophagy: a type of cell death induced by some oxysterols.

Nury T, Zarrouk A, Yammine A, Mackrill JJ, Vejux A, Lizard G

Br. J. Pharmacol.. 2020 Jun 24;:

Prevention of 7-Ketocholesterol-Induced Overproduction of Reactive Oxygen Species, Mitochondrial Dysfunction and Cell Death with Major Nutrients (Polyphenols, ω3 and ω9 Unsaturated Fatty Acids) of the Mediterranean Diet on N2a Neuronal Cells.

Yammine A, Nury T, Vejux A, Latruffe N, Vervandier-Fasseur D, Samadi M, Greige-Gerges H, Auezova L, Lizard G

Molecules. 2020 May 13;25(10):

Silymarin and Cancer: A Dual Strategy in Both in Chemoprevention and Chemosensitivity.

Delmas D, Xiao J, Vejux A, Aires V

Molecules. 2020 Apr 25;25(9):

Lipids Nutrients in Parkinson and Alzheimer's Diseases: Cell Death and Cytoprotection.

Nury T, Lizard G, Vejux A

Int J Mol Sci. 2020 Apr 3;21(7):

Docosahexaenoic Acid Attenuates Mitochondrial Alterations and Oxidative Stress Leading to Cell Death Induced by Very Long-Chain Fatty Acids in a Mouse Oligodendrocyte Model.

Nury T, Doria M, Lizard G, Vejux A

Int J Mol Sci. 2020 Jan 18;21(2):

7-Ketocholesterol- and 7β-Hydroxycholesterol-Induced Peroxisomal Disorders in Glial, Microglial and Neuronal Cells: Potential Role in Neurodegeneration : 7-ketocholesterol and 7β-hydroxycholesterol-Induced Peroxisomal Disorders and Neurodegeneration.

Nury T, Yammine A, Menetrier F, Zarrouk A, Vejux A, Lizard G

Adv Exp Med Biol. 2020 ;1299:31-41

Potential Involvement of Peroxisome in Multiple Sclerosis and Alzheimer's Disease : Peroxisome and Neurodegeneration.

Zarrouk A, Nury T, El Hajj HI, Gondcaille C, Andreoletti P, Moreau T, Cherkaoui-Malki M, Berger J, Hammami M, Lizard G, Vejux A

Adv Exp Med Biol. 2020 ;1299:91-104

7-ketocholesterol and 7β-hydroxycholesterol: in vitro and animal models used to characterize their activities and to identify molecules preventing their toxicity.

Vejux A, Abed-Vieillard D, Hajji K, Zarrouk A, Mackrill JJ, Ghosh S, Nury T, Yammine A, Zaibi M, Mihoubi W, Bouchab H, Nasser B, Grosjean Y, Lizard G

Biochem. Pharmacol.. 2019 Oct 3;:113648

Peroxisomes in Immune Response and Inflammation.

Di Cara F, Andreoletti P, Trompier D, Vejux A, Bülow MH, Sellin J, Lizard G, Cherkaoui-Malki M, Savary S

Int J Mol Sci. 2019 Aug 8;20(16):

Dimethyl fumarate and monomethyl fumarate attenuate oxidative stress and mitochondrial alterations leading to oxiapoptophagy in 158N murine oligodendrocytes treated with 7β-hydroxycholesterol.

Sghaier R, Nury T, Leoni V, Caccia C, Pais De Barros JP, Cherif A, Vejux A, Moreau T, Lime K, Samadi M, Mackrill JJ, Masmoudi AS, Lizard G, Zarrouk A

J. Steroid Biochem. Mol. Biol.. 2019 Jul 22;:105432

Biotin attenuation of oxidative stress, mitochondrial dysfunction, lipid metabolism alteration and 7β-hydroxycholesterol-induced cell death in 158N murine oligodendrocytes.

Sghaier R, Zarrouk A, Nury T, Ilham B, O'Brien N, Mackrill JJ, Vejux A, Samadi M, Nasser B, Caccia C, Leoni V, Moreau T, Cherkaoui-Malki M, Salhedine Masmoudi A, Lizard G

Free Radic. Res.. 2019 May 1;:1-11

Induction of a non-apoptotic mode of cell death associated with autophagic characteristics with steroidal maleic anhydrides and 7β-hydroxycholesterol on glioma cells.

Sassi K, Nury T, Zarrouk A, Sghaier R, Khalafi-Nezhad A, Vejux A, Samadi M, Aissa-Fennira FB, Lizard G

J. Steroid Biochem. Mol. Biol.. 2019 Apr 26;:

Protective function of autophagy during VLCFA-induced cytotoxicity in a neurodegenerative cell model.

Doria M, Nury T, Delmas D, Moreau T, Lizard G, Vejux A

Free Radic. Biol. Med.. 2019 Apr 17;:

Induction of Neuronal Differentiation of Murine N2a Cells by Two Polyphenols Present in the Mediterranean Diet Mimicking Neurotrophins Activities: Resveratrol and Apigenin.

Namsi A, Nury T, Hamdouni H, Yammine A, Vejux A, Vervandier-Fasseur D, Latruffe N, Masmoudi-Kouki O, Lizard G

Diseases. 2018 Jul 22;6(3):

Cytoprotective Activities of Milk Thistle Seed Oil Used in Traditional Tunisian Medicine on 7-Ketocholesterol and 24S-Hydroxycholesterol-Induced Toxicity on 158N Murine Oligodendrocytes.

Meddeb W, Rezig L, Zarrouk A, Nury T, Vejux A, Prost M, Bretillon L, Mejri M, Lizard G

Antioxidants (Basel). 2018 Jul 19;7(7):

Induction of peroxisomal changes in oligodendrocytes treated with 7-ketocholesterol: Attenuation by α-tocopherol.

Nury T, Sghaier R, Zarrouk A, Ménétrier F, Uzun T, Leoni V, Caccia C, Meddeb W, Namsi A, Sassi K, Mihoubi W, Riedinger JM, Cherkaoui-Malki M, Moreau T, Vejux A, Lizard G

Biochimie. 2018 Jul 19;:

Prevention of 7-ketocholesterol-induced side effects by natural compounds.

Brahmi F, Vejux A, Sghaier R, Zarrouk A, Nury T, Meddeb W, Rezig L, Namsi A, Sassi K, Yammine A, Badreddine I, Vervandier-Fasseur D, Madani K, Boulekbache-Makhlouf L, Nasser B, Lizard G

Crit Rev Food Sci Nutr. 2018 Jul 11;:1-48

The effect of oxysterols on nerve impulses.

Bezine M, Namsi A, Sghaier R, Ben Khalifa R, Hamdouni H, Brahmi F, Badreddine I, Mihoubi W, Nury T, Vejux A, Zarrouk A, de Sèze J, Moreau T, Nasser B, Lizard G

Biochimie. 2018 Apr 21;:

Modulation of Kv3.1b potassium channel level and intracellular potassium concentration in 158N murine oligodendrocytes and BV-2 murine microglial cells treated with 7-ketocholesterol, 24S-hydroxycholesterol or tetracosanoic acid (C24:0).

Bezine M, Maatoug S, Ben Khalifa R, Debbabi M, Zarrouk A, Wang Y, Griffiths WJ, Nury T, Samadi M, Vejux A, de Sèze J, Moreau T, Kharrat R, El Ayeb M, Lizard G

Biochimie. 2018 Feb 17;:

Biomarkers of Amyotrophic Lateral Sclerosis: Current Status and Interest of Oxysterols and Phytosterols.

Vejux A, Namsi A, Nury T, Moreau T, Lizard G

Front Mol Neurosci. 2018 ;11:12

Evidence of biological activity of Mentha species extracts on apoptotic and autophagic targets on murine RAW264.7 and human U937 monocytic cells.

Brahmi F, Hadj-Ahmed S, Zarrouk A, Bezine M, Nury T, Madani K, Chibane M, Vejux A, Andreoletti P, Boulekbache-Makhlouf L, Lizard G

Pharm Biol. 2017 Dec;55(1):286-293

Argan Oil-Mediated Attenuation of Organelle Dysfunction, Oxidative Stress and Cell Death Induced by 7-Ketocholesterol in Murine Oligodendrocytes 158N.

Badreddine A, Zarrouk A, Karym EM, Debbabi M, Nury T, Meddeb W, Sghaier R, Bezine M, Vejux A, Martine L, Grégoire S, Bretillon L, Prost-Camus E, Durand P, Prost M, Moreau T, Cherkaoui-Malki M, Nasser B, Lizard G

Int J Mol Sci. 2017 Oct 23;18(10):

Evidence of K(+) homeostasis disruption in cellular dysfunction triggered by 7-ketocholesterol, 24S-hydroxycholesterol, and tetracosanoic acid (C24:0) in 158N murine oligodendrocytes.

Bezine M, Debbabi M, Nury T, Ben-Khalifa R, Samadi M, Cherkaoui-Malki M, Vejux A, Raas Q, de Sèze J, Moreau T, El-Ayeb M, Lizard G

Chem. Phys. Lipids. 2017 Mar;:

Flow Cytometric Analysis of the Expression Pattern of Peroxisomal Proteins, Abcd1, Abcd2, and Abcd3 in BV-2 Murine Microglial Cells.

Debbabi M, Nury T, Helali I, Karym EM, Geillon F, Gondcaille C, Trompier D, Najid A, Terreau S, Bezine M, Zarrouk A, Vejux A, Andreoletti P, Cherkaoui-Malki M, Savary S, Lizard G

Methods Mol. Biol.. 2017 ;1595:257-265

Contribution of cholesterol and oxysterols to the pathophysiology of Parkinson's disease.

Doria M, Maugest L, Moreau T, Lizard G, Vejux A

Free Radic. Biol. Med.. 2016 Dec;101:393-400

Protective Effects of α-Tocopherol, γ-Tocopherol and Oleic Acid, Three Compounds of Olive Oils, and No Effect of Trolox, on 7-Ketocholesterol-Induced Mitochondrial and Peroxisomal Dysfunction in Microglial BV-2 Cells.

Debbabi M, Nury T, Zarrouk A, Mekahli N, Bezine M, Sghaier R, Grégoire S, Martine L, Durand P, Camus E, Vejux A, Jabrane A, Bretillon L, Prost M, Moreau T, Ammou SB, Hammami M, Lizard G

Int J Mol Sci. 2016 Nov;17(12):

7-Ketocholesterol is increased in the plasma of X-ALD patients and induces peroxisomal modifications in microglial cells: Potential roles of 7-ketocholesterol in the pathophysiology of X-ALD.

Nury T, Zarrouk A, Ragot K, Debbabi M, Riedinger JM, Vejux A, Aubourg P, Lizard G

J. Steroid Biochem. Mol. Biol.. 2016 Apr;:

Mitochondrial dysfunctions in 7-ketocholesterol-treated 158N oligodendrocytes without or with α-tocopherol: Impacts on the cellular profil of tricarboxylic cycle-associated organic acids, long chain saturated and unsaturated fatty acids, oxysterols, chole

Leoni V, Nury T, Vejux A, Zarrouk A, Caccia C, Debbabi M, Fromont A, Sghaier R, Moreau T, Lizard G

J. Steroid Biochem. Mol. Biol.. 2016 Mar;:

Attenuation of 7-ketocholesterol-induced overproduction of reactive oxygen species, apoptosis, and autophagy by dimethyl fumarate on 158N murine oligodendrocytes.

Zarrouk A, Nury T, Karym EM, Vejux A, Sghaier R, Gondcaille C, Andreoletti P, Trompier D, Savary S, Cherkaoui-Malki M, Debbabi M, Fromont A, Riedinger JM, Moreau T, Lizard G

J. Steroid Biochem. Mol. Biol.. 2016 Feb;:

Induction of oxiapoptophagy on 158N murine oligodendrocytes treated by 7-ketocholesterol-, 7beta-hydroxycholesterol-, and 24(S)-hydroxycholesterol: Protective effects of alpha-tocopherol and docosahexaenoic acid (DHA; C22:6 n-3).

Nury T, Zarrouk A, Mackrill JJ, Samadi M, Durand P, Riedinger JM, Doria M, Vejux A, Limagne E, Delmas D, Prost M, Moreau T, Hammami M, Delage-Mourroux R, O'Brien NM, Lizard G

Steroids. 2015 Feb 12. pii: S0039-128X(15)00059-8

Involvement of oxysterols in age-related diseases and ageing processes.

Zarrouk A, Vejux A, Mackrill J, O'Callaghan Y, Hammami M, O'Brien N, Lizard G

Ageing Res Rev. 2014 Nov;18:148-62

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