Dr CHARVIN Gilles

Fiche personne

Coordonnées

IGBMC
1 rue Laurent Fries
BP 10142
67404 ILLKIRCH

03 88 65 33 33

Territoire

Alsace

Statut

Chercheur

Affiliation

IGBMC - Institut de génétique et de biologie moléculaire et cellulaire (IGBMC)

Équipes/plateformes

Equipe "Biologie du développement et cellules souches / Biophysique de la croissance et de la division cellulaire"

Publications

Both genome instability and replicative senescence stem from the shortest telomere in telomerase-negative cells.

Berardi P, Martinez-Fernandez V, Rat A, Rosas Bringas FR, Jolivet P, Langston R, Mattarocci S, Maes A, Aspert T, Zeinoun B, Casier K, Kazemier HG, Charvin G, Doumic M, Chang M, Teixeira MT

Nat Commun. 2026 03 15;:

A trade-off between stress resistance and tolerance underlies the adaptive response to hydrogen peroxide.

Jacquel B, Kavčič B, Aspert T, Matifas A, Kuehn A, Zhuravlev A, Byckov E, Morgan B, Julou T, Charvin G

Cell Syst. 2025 07 16;16(7):101320

High-Throughput Measurement of Single-Fission Yeast Cell Volume Using Fluorescence Exclusion.

Venkova L, García-Ruano D, Jain A, Charvin G, Coudreuse D

Methods Mol Biol. 2025 ;2862:7-32

Changed life course upon defective replication of ribosomal RNA genes.

Hattori M, Horigome C, Aspert T, Charvin G, Kobayashi T

Genes Genet Syst. 2023 03 2;:

Left-right asymmetry in oxidative stress sensing neurons in .

Quintin S, Charvin G

MicroPubl Biol. 2022 10 19;2022:

Distinct mechanisms underlie H2O2 sensing in C. elegans head and tail.

Quintin S, Aspert T, Ye T, Charvin G

PLoS One. 2022 09 29;17(9):e0274226

DetecDiv, a generalist deep-learning platform for automated cell division tracking and survival analysis.

Aspert T, Hentsch D, Charvin G

Elife. 2022 08 17;11:

A Microfluidic Platform for Tracking Individual Cell Dynamics during an Unperturbed Nutrients Exhaustion.

Aspert T, Jacquel B, Charvin G

Bio Protoc. 2022 07 20;12(14):

Nuclear pore complex acetylation regulates mRNA export and cell cycle commitment in budding yeast.

Gomar-Alba M, Pozharskaia V, Cichocki B, Schaal C, Kumar A, Jacquel B, Charvin G, Igual JC, Mendoza M

EMBO J. 2022 06 23;:e2021110271

DNA circles promote yeast ageing in part through stimulating the reorganization of nuclear pore complexes.

Meinema AC, Marzelliusardottir A, Mirkovic M, Aspert T, Lee SS, Charvin G, Barral Y

Elife. 2022 Apr 4;11:

Monitoring single-cell dynamics of entry into quiescence during an unperturbed lifecycle.

Jacquel B, Aspert T, Laporte D, Sagot I, Charvin G

Elife. 2021 Nov 1;10:

Increased levels of mitochondrial import factor Mia40 prevent the aggregation of polyQ proteins in the cytosol.

Schlagowski AM, Knöringer K, Morlot S, Sánchez Vicente A, Flohr T, Krämer L, Boos F, Khalid N, Ahmed S, Schramm J, Murschall LM, Haberkant P, Stein F, Riemer J, Westermann B, Braun RJ, Winklhofer KF, Charvin G, Herrmann JM

EMBO J. 2021 Jun 30;:e107913

Microfluidics for single-cell lineage tracking over time to characterize transmission of phenotypes in .

Bheda P, Aguilar-Gómez D, Kukhtevich I, Becker J, Charvin G, Kirmizis A, Schneider R

STAR Protoc. 2020 Dec 18;1(3):100228

Single-Cell Tracing Dissects Regulation of Maintenance and Inheritance of Transcriptional Reinduction Memory.

Bheda P, Aguilar-Gómez D, Becker NB, Becker J, Stavrou E, Kukhtevich I, Höfer T, Maerkl S, Charvin G, Marr C, Kirmizis A, Schneider R

Mol. Cell. 2020 May 1;:

Proteostasis collapse, a hallmark of aging, hinders the chaperone-Start network and arrests cells in G1.

Moreno DF, Jenkins K, Morlot S, Charvin G, Csikasz-Nagy A, Aldea M

Elife. 2019 09 13;8:

Excessive rDNA Transcription Drives the Disruption in Nuclear Homeostasis during Entry into Senescence in Budding Yeast.

Morlot S, Song J, Léger-Silvestre I, Matifas A, Gadal O, Charvin G

Cell Rep. 2019 07 9;28(2):408-422.e4

Self-Learning Microfluidic Platform for Single-Cell Imaging and Classification in Flow.

Constantinou I, Jendrusch M, Aspert T, Görlitz F, Schulze A, Charvin G, Knop M

Micromachines (Basel). 2019 May 9;10(5):

COSPLAY: An expandable toolbox for combinatorial and swift generation of expression plasmids in yeast.

Goulev Y, Matifas A, Heyer V, Reina-San-Martin B, Charvin G

PLoS ONE. 2019 ;14(8):e0220694

Adaptation to DNA damage checkpoint in senescent telomerase-negative cells promotes genome instability.

Coutelier H, Xu Z, Morisse MC, Lhuillier-Akakpo M, Pelet S, Charvin G, Dubrana K, Teixeira MT

Genes Dev.. 2018 12 1;32(23-24):1499-1513

Multiple inputs ensure yeast cell size homeostasis during cell cycle progression.

Garmendia-Torres C, Tassy O, Matifas A, Molina N, Charvin G

Elife. 2018 Jul 4;7:

Controllable stress patterns over multi-generation timescale in microfluidic devices.

Goulev Y, Matifas A, Charvin G

Methods Cell Biol.. 2018 ;147:29-40

Nonlinear feedback drives homeostatic plasticity in HO stress response.

Goulev Y, Morlot S, Matifas A, Huang B, Molin M, Toledano MB, Charvin G

Elife. 2017 04 18;6:

Kinetics of Formation and Asymmetrical Distribution of Hsp104-Bound Protein Aggregates in Yeast.

Paoletti C, Quintin S, Matifas A, Charvin G

Biophys. J.. 2016 Apr 12;110(7):1605-1614

Two routes to senescence revealed by real-time analysis of telomerase-negative single lineages.

Xu Z, Fallet E, Paoletti C, Fehrmann S, Charvin G, Teixeira MT

Nat Commun. 2015 Jul 9;6:7680

Oscillatory Flow Modulates Mechanosensitive klf2a Expression through trpv4 and trpp2 during Heart Valve Development.

Heckel E, Boselli F, Roth S, Krudewig A, Belting HG, Charvin G, Vermot J

Curr. Biol.. 2015 May;25(10):1354-61

A quantitative approach to study endothelial cilia bending stiffness during blood flow mechanodetection in vivo.

Boselli F, Goetz JG, Charvin G, Vermot J

Methods Cell Biol.. 2015 ;127:161-73

In silico control of biomolecular processes.

Uhlendorf J, Miermont A, Delaveau T, Charvin G, Fages F, Bottani S, Hersen P, Batt G

Methods Mol. Biol.. 2015 ;1244:277-85

A memory system of negative polarity cues prevents replicative aging.

Meitinger F, Khmelinskii A, Morlot S, Kurtulmus B, Palani S, Andres-Pons A, Hub B, Knop M, Charvin G, Pereira G

Cell. 2014 Nov 20;159(5):1056-1069

Endothelial cilia mediate low flow sensing during zebrafish vascular development.

Goetz JG, Steed E, Ferreira RR, Roth S, Ramspacher C, Boselli F, Charvin G, Liebling M, Wyart C, Schwab Y, Vermot J

Cell Rep. 2014 Mar;6(5):799-808

Pulse propagation by a capacitive mechanism drives embryonic blood flow.

Anton H, Harlepp S, Ramspacher C, Wu D, Monduc F, Bhat S, Liebling M, Paoletti C, Charvin G, Freund JB, Vermot J

Development. 2013 Nov;140(21):4426-34

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