Mr MORLET Bastien

Fiche personne

Coordonnées

IGBMC
Plateforme de protéomique
1 rue Laurent Fries
BP 10142
67404 ILLKIRCH

Territoire

Alsace

Statut

Ingénieur/Technicien

Affiliation

IGBMC - Institut de génétique et de biologie moléculaire et cellulaire (IGBMC)

Équipes/plateformes

Plateforme de protéomique et de spectrométrie de masse de l’IGBMC (PPSMI)

Recherche

Expertises :
- Plateforme:Protéomique

Publications

Mapping the Brain Interaction Network of the Dual-Specificity, Tyrosine Phosphorylation-Regulated Kinase 1A (DYRK1A) Targeted by Leucettinib-21 Using Affinity Chromatography.

Deau E, Simon C, Hogrel G, Caillette J, Dairou J, Herault Y, Morlet B, Miyata Y, Meijer L, Lindberg MF

ACS Pharmacol Transl Sci. 2026 05 8;9(5):1204-1227

Quantitative analysis of DNA-GATA1 binding alterations linked to hematopoietic disorders.

Zambo B, Morlet B, Negroni L, Mózner O, Sarkadi B, Travé G, Gogl G

FEBS J. 2026 03 17;:

GGC repeat expansions within new open reading frames are translated into toxic polyglycine proteins in oculopharyngodistal myopathy.

Boivin M, Yu J, Eura N, Schmitt L, Pietri D, Grandgirard E, Goetz-Reiner P, Plassard D, Nahy C, Maglott A, Morlet B, Gao C, Lefebvre E, Philipps M, Eberling P, Pichot A, Rossolillo P, Thibault C, Oulad-Abdelghani M, Nishino I, Yang K, Wang N, Wang Z, Deng J, Charlet-Berguerand N

Nat Genet. 2026 02 17;:

Disrupted transcriptional networks regulated by CHD1L during neurodevelopment underlie the mirrored neuroanatomical and growth phenotypes of the 1q21.1 copy number variant.

Lemée MV, Loviglio MN, Ye T, Tilly P, Keime C, Weber C, Petrova A, Klein P, Morlet B, Wendling O, Jacobs H, Tharreau M, Geneviève D, Godin JD, Romier C, Duteil D, Golzio C

Nucleic Acids Res. 2025 09 23;53(18):

RNA polymerase II transcription initiation in holo-TFIID-depleted mouse embryonic stem cells.

Hisler V, Bardot P, Detilleux D, Bernardini A, Stierle M, Sanchez EG, Richard C, Arab LH, Ehrhard C, Morlet B, Hadzhiev Y, Jung M, Le Gras S, Négroni L, Müller F, Tora L, Vincent SD

Cell Rep. 2024 09 30;43(10):114791

Uncovering the BIN1-SH3 interactome underpinning centronuclear myopathy.

Zambo B, Edelweiss E, Morlet B, Negroni L, Pajkos M, Dosztanyi Z, Ostergaard S, Trave G, Laporte J, Gogl G

Elife. 2024 07 12;13:

Comparative analysis of PDZ-binding motifs in the diacylglycerol kinase family.

Zambo B, Gogl G, Morlet B, Eberling P, Negroni L, Moine H, Travé G

FEBS J. 2023 11 9;:

ATAC and SAGA co-activator complexes utilize co-translational assembly, but their cellular localization properties and functions are distinct.

Yayli G, Bernardini A, Mendoza Sanchez PK, Scheer E, Damilot M, Essabri K, Morlet B, Negroni L, Vincent SD, Timmers HTM, Tora L

Cell Rep. 2023 09 7;42(9):113099

HELZ2: a new, interferon-regulated, human 3'-5' exoribonuclease of the RNB family is expressed from a non-canonical initiation codon.

Huntzinger E, Sinteff J, Morlet B, Séraphin B

Nucleic Acids Res. 2023 08 21;:

The kinesin Kif21b regulates radial migration of cortical projection neurons through a non-canonical function on actin cytoskeleton.

Rivera Alvarez J, Asselin L, Tilly P, Benoit R, Batisse C, Richert L, Batisse J, Morlet B, Levet F, Schwaller N, Mély Y, Ruff M, Reymann AC, Godin JD

Cell Rep. 2023 07 6;42(7):112744

Hierarchical TAF1-dependent co-translational assembly of the basal transcription factor TFIID.

Bernardini A, Mukherjee P, Scheer E, Kamenova I, Antonova S, Mendoza Sanchez PK, Yayli G, Morlet B, Timmers HTM, Tora L

Nat Struct Mol Biol. 2023 06 29;:

Native holdup (nHU) to measure binding affinities from cell extracts.

Zambo B, Morlet B, Negroni L, Trave G, Gogl G

Sci Adv. 2022 12 21;8(51):eade3828

Quantitative fragmentomics allow affinity mapping of interactomes.

Gogl G, Zambo B, Kostmann C, Cousido-Siah A, Morlet B, Durbesson F, Negroni L, Eberling P, Jané P, Nominé Y, Zeke A, Østergaard S, Monsellier É, Vincentelli R, Travé G

Nat Commun. 2022 09 17;13(1):5472

Androgen receptor-mediated transcriptional repression targets cell plasticity in prostate cancer.

Erdmann É, Ould Madi Berthélémy P, Cottard F, Angel CZ, Schreyer E, Ye T, Morlet B, Negroni L, Kieffer B, Céraline J

Mol Oncol. 2021 Dec 17;:

Translation of GGC repeat expansions into a toxic polyglycine protein in NIID defines a novel class of human genetic disorders: the polyG diseases.

Boivin M, Deng J, Pfister V, Grandgirard E, Oulad-Abdelghani M, Morlet B, Ruffenach F, Negroni L, Koebel P, Jacob H, Riet F, Dijkstra AA, McFadden K, Clayton WA, Hong D, Miyahara H, Iwasaki Y, Sone J, Wang Z, Charlet-Berguerand N

Neuron. 2021 Apr 13;:

Novel Function of Bluetongue Virus NS3 Protein in Regulation of the MAPK/ERK Signaling Pathway.

Kundlacz C, Pourcelot M, Fablet A, Amaral Da Silva Moraes R, Léger T, Morlet B, Viarouge C, Sailleau C, Turpaud M, Gorlier A, Breard E, Lecollinet S, van Rijn PA, Zientara S, Vitour D, Caignard G

J. Virol.. 2019 Aug 15;93(16):