Dr BLAISE Sébastien

Fiche personne

Coordonnées

UMR CNRS/URCA 7369 MEDyC
UFR Sciences Exactes et Naturelles
Campus du Moulin de la Housse
BP 1039
51687 REIMS Cedex 2

Territoire

Alsace

Statut

Enseignant-Chercheur

Affiliation

Université de Reims Champagne-Ardenne (URCA)

UMR CNRS 7369 MEDyC - Matrice Extracellulaire et Dynamique Cellulaire MEDyC (MEDyC)

Équipes/plateformes

UMR 7369 MEDyC - Equipe "Vieillissement matriciel et remodelage vasculaire"

Publications

Novel Bioactive Multifunctional Polyphenols: A Chemo-Enzymatic Approach.

Flourat AL, Thiébault E, Martinez A, Brunissen F, Dosso A, Oszust F, Blaise S, Romier B, Allais F

Chemistry. 2025 12 26;:e03176

Minoxidil and nebivolol restore aortic elastic fiber homeostasis in diabetic mice via potassium channel activation.

Henry A, Vanalderwiert L, Oszust F, Wahart A, Carvajal Berrio DA, Brauchle EM, Schenke-Layland K, Brinckmann J, Steenbock H, Debelle L, Six I, Faury G, Jaisson S, Gillery P, Durlarch V, Sartelet H, Maurice P, Bennasroune A, Martiny L, Duca L, Romier B, Blaise S

Front Physiol. 2025 09 18;16:1648727

Hobnail hemangioma.

Cuypers A, Blaise S

Ann Dermatol Venereol. 2025 03 10;152(2):103343

Exploring aortic stiffness in aging mice: a comprehensive methodological overview.

Vanalderwiert L, Henry A, de Souza E Silva JM, Carvajal-Berrio D, Debelle L, Wahart A, Marzi J, Schenke-Layland K, Faury G, Six I, Schmelzer CEH, Brinckmann J, Steenbock H, Almagro S, Delacoux F, Jaisson S, Gillery P, Maurice P, Sartelet H, Bennasroune A, Duca L, Romier B, Blaise S

Aging (Albany NY). 2024 12 2;null:

METABOLIC SYNDROME-ASSOCIATED MURINE AORTIC WALL STIFFENING IS ASSOCIATED WITH PREMATURE ELASTIC FIBERS AGING.

Vanalderwiert L, Henry A, Wahart A, Carvajal Berrio DA, Brauchle EM, El Kaakour L, Schenke-Layland K, Brinckmann J, Steenbock H, Debelle L, Six I, Faury G, Jaisson S, Gillery P, Durlach V, Sartelet H, Maurice P, Bennasroune A, Martiny L, Duca L, Romier B, Blaise S

Am J Physiol Cell Physiol. 2024 07 1;:

Inhibition of neuraminidase-1 sialidase activity by interfering peptides impairs insulin receptor activity in vitro and glucose homeostasis in vivo.

Toussaint K, Appert-Collin A, Vanalderwiert L, Bour C, Terryn C, Spenlé C, Van Der Heyden M, Roumieux M, Maurice P, Romier-Crouzet B, Sartelet H, Duca L, Blaise S, Bennasroune A

J Biol Chem. 2024 04 23;:107316

Sialic acids cleavage induced by elastin-derived peptides impairs the interaction between insulin and its receptor in adipocytes 3T3-L1.

Guillot A, Toussaint K, Ebersold L, ElBtaouri H, Thiebault E, Issad T, Peiretti F, Maurice P, Sartelet H, Bennasroune A, Martiny L, Dauchez M, Duca L, Durlach V, Romier B, Baud S, Blaise S

J Physiol Biochem. 2024 02 23;:

Neuraminidase-1: A Sialidase Involved in the Development of Cancers and Metabolic Diseases.

Toussaint K, Appert-Collin A, Morjani H, Albrecht C, Sartelet H, Romier-Crouzet B, Maurice P, Duca L, Blaise S, Bennasroune A

Cancers (Basel). 2022 10 5;14(19):

Early Alterations of Intra-Mural Elastic Lamellae Revealed by Synchrotron X-ray Micro-CT Exploration of Diabetic Aortas.

Ben Zemzem A, Liang X, Vanalderwiert L, Bour C, Romier-Crouzet B, Blaise S, Sherratt MJ, Weitkamp T, Dauchez M, Baud S, Passat N, Debelle L, Almagro S

Int J Mol Sci. 2022 Mar 17;23(6):

The Elastin Receptor Complex: An Emerging Therapeutic Target Against Age-Related Vascular Diseases.

Tembely D, Henry A, Vanalderwiert L, Toussaint K, Bennasroune A, Blaise S, Sartelet H, Jaisson S, Galés C, Martiny L, Duca L, Romier-Crouzet B, Maurice P

Front Endocrinol (Lausanne). 2022 ;13:815356

Characterization of novel interactions with membrane NEU1 highlights new regulatory functions for the Elastin Receptor Complex in monocyte interaction with endothelial cells.

Bocquet O, Tembely D, Rioult D, Terryn C, Romier B, Bennasroune A, Blaise S, Sartelet H, Martiny L, Duca L, Maurice P

Cell Biosci. 2021 Dec 13;11(1):206

Apelin expression deficiency in mice contributes to vascular stiffening by extracellular matrix remodeling of the aortic wall.

Romier B, Dray C, Vanalderwiert L, Wahart A, Hocine T, Dortignac A, Garbar C, Garbar C, Boulagnon C, Bouland N, Maurice P, Bennasroune A, Sartelet H, Martiny L, Duca L, Valet P, Blaise S

Sci Rep. 2021 Nov 15;11(1):22278

X-ray microtomography reveals a lattice-like network within aortic elastic lamellae.

Ben Zemzem A, Genevaux A, Wahart A, Bodey AJ, Blaise S, Romier-Crouzet B, Jonquet J, Bour C, Cogranne R, Beauseroy P, Dauchez M, Sherratt MJ, Debelle L, Almagro S

FASEB J. 2021 Oct;35(10):e21844

Fetal Programming by Methyl Donor Deficiency Produces Pathological Remodeling of the Ascending Aorta.

Balint B, Hergalan S, Camadro JM, Blaise S, Vanalderwiert L, Lignières L, Guéant-Rodriguez RM, Guéant JL

Arterioscler Thromb Vasc Biol. 2021 Apr 8;:ATVBAHA120315587

Adverse effects of oseltamivir phosphate therapy on the liver of LDLR-/- mice without any benefit on atherosclerosis and thrombosis.

Bocquet O, Wahart A, Sarazin T, Vincent E, Schneider C, Fougerat A, Gayral S, Henry A, Blaise S, Romier-Crouzet B, Boulagnon C, Jaisson S, Gillery PP, Bennasroune A, Sartelet H, Laffargue M, Martiny PL, Duca PL, Maurice P

J Cardiovasc Pharmacol. 2021 Feb 25;:

Revealing the elasticity of an individual aortic fiber during ageing at nanoscale by atomic force microscopy.

Berquand A, Wahart A, Henry A, Gorisse L, Maurice P, Blaise S, Romier-Crouzet B, Pietrement C, Bennasroune A, Sartelet H, Jaisson S, Gillery P, Martiny L, Touré F, Duca L, Molinari M

Nanoscale. 2021 Jan 5;:

Lactosylceramide induced by elastin-derived peptides decreases adipocyte differentiation.

Hocine T, Blaise S, Hachet C, Guillot A, Sartelet H, Maurice P, Bennasroune A, Martiny L, Duca L, Romier-Crouzet B, El Btaouri H

J. Physiol. Biochem.. 2020 Jun 26;:

Transmembrane Peptides as a New Strategy to Inhibit Neuraminidase-1 Activation.

Albrecht C, Kuznetsov AS, Appert-Collin A, Dhaideh Z, Callewaert M, Bershatsky YV, Urban AS, Bocharov EV, Bagnard D, Baud S, Blaise S, Romier-Crouzet B, Efremov RG, Dauchez M, Duca L, Gueroult M, Maurice P, Bennasroune A

Front Cell Dev Biol. 2020 ;8:611121

Transmembrane Peptides as Inhibitors of Protein-Protein Interactions: An Efficient Strategy to Target Cancer Cells?

Albrecht C, Appert-Collin A, Bagnard D, Blaise S, Romier-Crouzet B, Efremov RG, Sartelet H, Duca L, Maurice P, Bennasroune A

Front Oncol. 2020 ;10:519

Umbrella Visualization: a method of analysis dedicated to glycan flexibility with UnityMol.

Besançon C, Guillot A, Blaise S, Dauchez M, Belloy N, Prévoteau-Jonquet J, Baud S

Methods. 2019 Jul 11;:

Elastic fibers and elastin receptor complex: Neuraminidase-1 takes the center stage.

Bennasroune A, Romier-Crouzet B, Blaise S, Laffargue M, Efremov RG, Martiny L, Maurice P, Duca L

Matrix Biol.. 2019 Jun 18;:

Role of Elastin Peptides and Elastin Receptor Complex in metabolic and cardiovascular diseases.

Wahart A, Hocine T, Albrecht C, Henry A, Sarazin T, Martiny L, Btaouri HE, Maurice P, Bennasroune A, Romier-Crouzet B, Blaise S, Duca L

FEBS J.. 2019 Apr 4;:

Identification of CD36 as a new interaction partner of membrane NEU1: potential implication in the pro-atherogenic effects of the elastin receptor complex.

Kawecki C, Bocquet O, Schmelzer CEH, Heinz A, Ihling C, Wahart A, Romier B, Bennasroune A, Blaise S, Terryn C, Linton KJ, Martiny L, Duca L, Maurice P

Cell. Mol. Life Sci.. 2018 Nov 29;:

Production of Elastin-Derived Peptides Contribute to the Development of Non-Alcoholic Steatohepatitis.

Romier B, Ivaldi C, Sartelet H, Heinz A, Schmelzer CEH, Garnotel R, Guillot A, Jonquet J, Bertin E, Guéant JL, Alberto JM, Bronowicki JP, Amoyel J, Hocine T, Duca L, Maurice P, Bennasroune A, Martiny L, Debelle L, Durlach V, Blaise S

Diabetes. 2018 May 25;:

New Insights into Molecular Organization of Human Neuraminidase-1: Transmembrane Topology and Dimerization Ability.

Maurice P, Baud S, Bocharova OV, Bocharov EV, Kuznetsov AS, Kawecki C, Bocquet O, Romier B, Gorisse L, Ghirardi M, Duca L, Blaise S, Martiny L, Dauchez M, Efremov RG, Debelle L

Sci Rep. 2016 Dec;6:38363

Impact of sialic acids on the molecular dynamic of bi-antennary and tri-antennary glycans.

Guillot A, Dauchez M, Belloy N, Jonquet J, Duca L, Romier B, Maurice P, Debelle L, Martiny L, Durlach V, Baud S, Blaise S

Sci Rep. 2016 Oct;6:35666

Matrix ageing and vascular impacts: focus on elastin fragmentation.

Duca L, Blaise S, Romier B, Laffargue M, Gayral S, El Btaouri H, Kawecki C, Guillot A, Martiny L, Debelle L, Maurice P

Cardiovasc. Res.. 2016 06;110(3):298-308

Matrix metalloproteinase 11 protects from diabesity and promotes metabolic switch.

Dali-Youcef N, Hnia K, Blaise S, Messaddeq N, Blanc S, Postic C, Valet P, Tomasetto C, Rio MC

Sci Rep. 2016 Apr;6:25140

The Elastin Receptor Complex: A Unique Matricellular Receptor with High Anti-tumoral Potential.

Scandolera A, Odoul L, Salesse S, Guillot A, Blaise S, Kawecki C, Maurice P, El Btaouri H, Romier-Crouzet B, Martiny L, Debelle L, Duca L

Front Pharmacol. 2016 ;7:32

Uncoupling of Elastin Complex Receptor during In Vitro Aging Is Related to Modifications in Its Intrinsic Sialidase Activity and the Subsequent Lactosylceramide Production.

Scandolera A, Rabenoelina F, Chaintreuil C, Rusciani A, Maurice P, Blaise S, Romier-Crouzet B, El Btaouri H, Martiny L, Debelle L, Duca L

PLoS One. 2015 Jun 18;10(6):e0129994

Elastin-derived peptides are new regulators of thrombosis.

Kawecki C, Hezard N, Bocquet O, Poitevin G, Rabenoelina F, Kauskot A, Duca L, Blaise S, Romier B, Martiny L, Nguyen P, Debelle L, Maurice P

Arterioscler Thromb Vasc Biol. 2014 Dec;34(12):2570-8

Elastin-derived peptides potentiate atherosclerosis through the immune Neu1-PI3Kgamma pathway.

Gayral S, Garnotel R, Castaing-Berthou A, Blaise S, Fougerat A, Berge E, Montheil A, Malet N, Wymann MP, Maurice P, Debelle L, Martiny L, Martinez LO, Pshezhetsky AV, Duca L, Laffargue M

Cardiovasc Res. 2014 Apr 1;102(1):118-27

Elastin-derived peptides are new regulators of insulin resistance development in mice.

Blaise S, Romier B, Kawecki C, Ghirardi M, Rabenoelina F, Baud S, Duca L, Maurice P, Heinz A, Schmelzer CE, Tarpin M, Martiny L, Garbar C, Dauchez M, Debelle L, Durlach V

Diabetes. 2013 Nov;62(11):3807-16

Interaction between the elastin peptide VGVAPG and human elastin binding protein.

Blanchevoye C, Floquet N, Scandolera A, Baud S, Maurice P, Bocquet O, Blaise S, Ghoneim C, Cantarelli B, Delacoux F, Dauchez M, Efremov RG, Martiny L, Duca L, Debelle L

J Biol Chem. 2013 Jan 11;288(2):1317-28

Methyl donor deficiency impairs fatty acid oxidation through PGC-1α hypomethylation and decreased ER-α, ERR-α, and HNF-4α in the rat liver.

Pooya S, Blaise S, Moreno Garcia M, Giudicelli J, Alberto JM, Guéant-Rodriguez RM, Jeannesson E, Gueguen N, Bressenot A, Nicolas B, Malthiery Y, Daval JL, Peyrin-Biroulet L, Bronowicki JP, Guéant JL

J. Hepatol.. 2012 Aug;57(2):344-51