Dr OULAD-ABDELGHANI Mustapha

Fiche personne

Coordonnées

IGBMC
1 rue Laurent Fries
BP 10142
67404 ILLKIRCH

03 88 65 33 70

Territoire

Alsace

Statut

Ingénieur/Technicien

Affiliation

IGBMC - Institut de génétique et de biologie moléculaire et cellulaire (IGBMC)

Équipes/plateformes

Anticorps

Publications

GGC repeat expansions within new open reading frames are translated into toxic polyglycine proteins in oculopharyngodistal myopathy.

Boivin M, Yu J, Eura N, Schmitt L, Pietri D, Grandgirard E, Goetz-Reiner P, Plassard D, Nahy C, Maglott A, Morlet B, Gao C, Lefebvre E, Philipps M, Eberling P, Pichot A, Rossolillo P, Thibault C, Oulad-Abdelghani M, Nishino I, Yang K, Wang N, Wang Z, Deng J, Charlet-Berguerand N

Nat Genet. 2026 02 17;:

In immune-mediated necrotising myopathy, anti-HMGCR antibodies inhibit HMGCR activity, leading to the sarcoplasmic accumulation of lipid droplets and myofibres necrosis.

Giannini M, Quiring G, Oulad-Abdelghani M, Lannes B, Allenbach Y, Benveniste O, Boyer O, Pakleza AN, Geny B, Meyer A

Ann Rheum Dis. 2025 05 22;:

Experimental myositis: an optimised version of C-protein-induced myositis.

Giannini M, Rovito D, Oulad-Abdelghani M, Messaddeq N, Debrut L, Quiring G, Kessler P, Charles AL, Geny B, Metzger D, Laverny G, Meyer A

RMD Open. 2025 03 5;11(1):

Droplet Surface Immunoassay by Relocation (D-SIRe) for High-Throughput Analysis of Cytosolic Proteins at the Single-Cell Level.

Dufossez R, Ursuegui S, Baudrey S, Pernod K, Mouftakhir S, Oulad-Abdelghani M, Mosser M, Chaubet G, Ryckelynck M, Wagner A

Anal Chem. 2023 02 23;:

Differential impact of ubiquitous and muscle dynamin 2 isoforms in muscle physiology and centronuclear myopathy.

Gómez-Oca R, Edelweiss E, Djeddi S, Gerbier M, Massana-Muñoz X, Oulad-Abdelghani M, Crucifix C, Spiegelhalter C, Messaddeq N, Poussin-Courmontagne P, Koebel P, Cowling BS, Laporte J

Nat Commun. 2022 11 11;13(1):6849

Context-dependent function of TSLP and IL-1β in skin allergic sensitization and atopic march.

Segaud J, Yao W, Marschall P, Daubeuf F, Lehalle C, German B, Meyer P, Hener P, Hugel C, Flatter E, Guivarch M, Clauss L, Martin SF, Oulad-Abdelghani M, Li M

Nat Commun. 2022 09 1;13(1):4703

Wnt5a Promotes Lysosomal Cholesterol Egress and Protects Against Atherosclerosis.

Awan S, Lambert M, Imtiaz A, Alpy F, Tomasetto C, Oulad-Abdelghani M, Schaeffer C, Moritz C, Julien-David D, Najib S, Martinez LO, Matz RL, Collet X, Silva-Rojas R, Böhm J, Herz J, Terrand J, Boucher P

Circ Res. 2021 Dec 10;:

A Novel Nanobody Precisely Visualizes Phosphorylated Histone H2AX in Living Cancer Cells under Drug-Induced Replication Stress.

Moeglin E, Desplancq D, Stoessel A, Massute C, Ranniger J, McEwen AG, Zeder-Lutz G, Oulad-Abdelghani M, Chiper M, Lafaye P, Di Ventura B, Didier P, Poterszman A, Weiss E

Cancers (Basel). 2021 Jul 1;13(13):

Translation of GGC repeat expansions into a toxic polyglycine protein in NIID defines a novel class of human genetic disorders: the polyG diseases.

Boivin M, Deng J, Pfister V, Grandgirard E, Oulad-Abdelghani M, Morlet B, Ruffenach F, Negroni L, Koebel P, Jacob H, Riet F, Dijkstra AA, McFadden K, Clayton WA, Hong D, Miyahara H, Iwasaki Y, Sone J, Wang Z, Charlet-Berguerand N

Neuron. 2021 Apr 13;:

Distribution of Parkinson's disease associated RAB39B in mouse brain tissue.

Gao Y, Wilson GR, Stephenson SEM, Oulad-Abdelghani M, Charlet-Berguerand N, Bozaoglu K, McLean CA, Thomas PQ, Finkelstein DI, Lockhart PJ

Mol Brain. 2020 Mar 30;13(1):52

Uniform Widespread Nuclear Phosphorylation of Histone H2AX Is an Indicator of Lethal DNA Replication Stress.

Moeglin E, Desplancq D, Conic S, Oulad-Abdelghani M, Stoessel A, Chiper M, Vigneron M, Didier P, Tora L, Weiss E

Cancers (Basel). 2019 Mar 13;11(3):

Novel antibodies reveal presynaptic localization of C9orf72 protein and reduced protein levels in C9orf72 mutation carriers.

Frick P, Sellier C, Mackenzie IRA, Cheng CY, Tahraoui-Bories J, Martinat C, Pasterkamp RJ, Prudlo J, Edbauer D, Oulad-Abdelghani M, Feederle R, Charlet-Berguerand N, Neumann M

Acta Neuropathol Commun. 2018 Aug 3;6(1):72

Imaging of native transcription factors and histone phosphorylation at high resolution in live cells.

Conic S, Desplancq D, Ferrand A, Fischer V, Heyer V, Reina San Martin B, Pontabry J, Oulad-Abdelghani M, Babu N K, Wright GD, Molina N, Weiss E, Tora L

J. Cell Biol.. 2018 Apr 2;217(4):1537-1552

In vitro hydroquinone-induced instauration of histone bivalent mark on human retroelements (LINE-1) in HL60 cells.

Mancini M, Mandruzzato M, Garzia AC, Sahnane N, Magnani E, Macchi F, Oulad-Abdelghani M, Oudet P, Bollati V, Fustinoni S, Furlan D, Bonapace IM

Toxicol In Vitro. 2017 Apr;40:1-10

Translation of Expanded CGG Repeats into FMRpolyG Is Pathogenic and May Contribute to Fragile X Tremor Ataxia Syndrome.

Sellier C, Buijsen RA, He F, Natla S, Jung L, Tropel P, Gaucherot A, Jacobs H, Meziane H, Vincent A, Champy MF, Sorg T, Pavlovic G, Wattenhofer-Donze M, Birling MC, Oulad-Abdelghani M, Eberling P, Ruffenach F, Joint M, Anheim M, Martinez-Cerdeno V, Tassone F, Willemsen R, Hukema RK, Viville S, Martinat C, Todd PK, Charlet-Berguerand N

Neuron. 2017 Jan;93(2):331-347

Loss of C9ORF72 impairs autophagy and synergizes with polyQ Ataxin-2 to induce motor neuron dysfunction and cell death.

Sellier C, Campanari ML, Julie Corbier C, Gaucherot A, Kolb-Cheynel I, Oulad-Abdelghani M, Ruffenach F, Page A, Ciura S, Kabashi E, Charlet-Berguerand N

EMBO J.. 2016 06 15;35(12):1276-97