Détail - canceropole-wordpress

Stoichiometric Antibody-Polymer-Drug Conjugate for Effective Low-Dose Treatment of Breast Cancer.

Lehot V, Lidický O, Most J, Nothisen M, Erb S, Dovgan I, Osypenko A, Koniev O, Kolodych S, Kotrchová L, Chaubet G, Cianférani S, Etrych T, Wagner A

Biomacromolecules. 2025 10 13;:

Antibody-Vincristine Conjugates as Potent Anticancer Therapeutic Agents.

Boos A, Most J, Cahuzac H, Moreira da Silva L, Daubeuf F, Erb S, Cianférani S, Hernandez-Alba O, Semenchenko C, Dovgan I, Kolodych S, Detappe A, Dantzer F, Wagner A, Zeniou M, Chaubet G

J Med Chem. 2024 12 16;:

Protocol to generate, purify, and analyze antibody-oligonucleotide conjugates from off-the-shelf antibodies.

Rady T, Lehot V, Most J, Erb S, Cianferani S, Chaubet G, Basse N, Wagner A

STAR Protoc. 2024 09 28;5(4):103329

Supramolecular Bioconjugation Strategy for Antibody-Targeted Delivery of siRNA.

Ripoll M, Cahuzac H, Dovgan I, Ursuegui S, Neuberg P, Erb S, Cianférani S, Kichler A, Remy JS, Wagner A

Bioconjug Chem. 2024 09 25;:

Retinoids Molecular Probes by Late-stage Azide Insertion - Functional Tools to Decrypt Retinoid Metabolism.

Coulleray J, Kindler A, Rima M, Cahuzac H, Rochel N, Chaubet G, Krezel W, Wagner A

Chembiochem. 2024 08 2;:e202300689

Targeted delivery of immune-stimulating bispecific RNA, inducing apoptosis and anti-tumor immunity in cancer cells.

Rady T, Erb S, Deddouche-Grass S, Morales R, Chaubet G, Cianférani S, Basse N, Wagner A

iScience. 2024 03 15;27(3):109068

Drug upgrade: A complete methodology from old drug to new chemical entities using Nematic Protein Organization Technique.

Eschbach J, Wagner A, Beahr C, Bekel A, Korganow AS, Quartier A, Peter JC, Eftekhari P

Drug Dev Res. 2024 02;85(1):e22151

Site-Selective Protein Conjugation by a Multicomponent Ugi Reaction.

Koutsopetras I, Vaur V, Benazza R, Diemer H, Sornay C, Ersoy Y, Rochet L, Longo C, Hernandez-Alba O, Erb S, Detappe A, Skerra A, Wagner A, Cianferani S, Chaubet G

Chemistry. 2023 12 5;:e202303242

Reinvestigation of the Automated Synthesis of Stoichiometrically Conjugated Antibodies to Access High Molecular Weight Payloads and Multiplexed Conjugation via an In-Solution Trans-Tagging Process.

Lehot V, Lidický O, Most J, Erb S, Dovgan I, Osypenko A, Koniev O, Kolodych S, Kotrchová L, Chaubet G, Cianférani S, Etrych T, Wagner A

ACS Omega. 2023 10 31;8(43):40508-40516

Microfluidic Droplet Stabilization via SPAAC Promoted Antibody Conjugation at the Water/Oil Interface.

Dufossez R, Krafft MP, Ursuegui S, Mosser M, Mouftakhir S, Pernod K, Chaubet G, Ryckelynck M, Wagner A

ACS Appl Mater Interfaces. 2023 09 13;:

Targeted Anticancer Agent with Original Mode of Action Prepared by Supramolecular Assembly of Antibody Oligonucleotide Conjugates and Cationic Nanoparticles.

Lehot V, Neuberg P, Ripoll M, Daubeuf F, Erb S, Dovgan I, Ursuegui S, Cianférani S, Kichler A, Chaubet G, Wagner A

Pharmaceutics. 2023 06 2;15(6):

A Novel Family of Acid-Cleavable Linker Based on Cyclic Acetal Motifs for the Production of Antibody-Drug Conjugates with High Potency and Selectivity.

Rady T, Turelli L, Nothisen M, Tobaldi E, Erb S, Thoreau F, Hernandez-Alba O, Cianferani S, Daubeuf F, Wagner A, Chaubet G

Bioconjug Chem. 2022 09 15;:

An overview of chemo- and site-selectivity aspects in the chemical conjugation of proteins.

Sornay C, Vaur V, Wagner A, Chaubet G

R Soc Open Sci. 2022 Jan;9(1):211563

Bicyclo[6.1.0]nonyne carboxylic acid for the production of stable molecular probes.

Rady T, Mosser M, Nothisen M, Erb S, Dovgan I, Cianférani S, Wagner A, Chaubet G

RSC Adv. 2021 Nov 10;11(58):36777-36780

Plasma induced acceleration and selectivity in strain-promoted azide-alkyne cycloadditions.

Warther D, Dursun E, Recher M, Ursuegui S, Mosser M, Sobska J, Krezel W, Chaubet G, Wagner A

Org Biomol Chem. 2021 May 24;:

Non-specific interactions of antibody-oligonucleotide conjugates with living cells.

Lehot V, Kuhn I, Nothisen M, Erb S, Kolodych S, Cianférani S, Chaubet G, Wagner A

Sci Rep. 2021 Mar 15;11(1):5881

Manniindole, an indole derivative from the roots of and combined antischistosomal and enzymatic activities.

Toussi Matchi JL, Tchamo Noungoue D, Kuhn I, Boissier J, Tchouankeu JC, Nothisen M, Chaubet G, Garnier D, Ursuegui S, Ngouela SA, Wagner A

Nat. Prod. Res.. 2020 Sep 28;:1-9

Investigating Ugi / Passerini multicomponent reactions for the Site-Selective Conjugation of Native Trastuzumab.

Sornay C, Hessmann S, Erb S, Dovgan I, Ehkirch A, Botzanowski T, Cianférani S, Wagner A, Chaubet G

Chemistry. 2020 Jun 26;:

On the use of DNA as a linker in antibody-drug conjugates: synthesis, stability and in vitro potency.

Dovgan I, Ehkirch A, Lehot V, Kuhn I, Koniev O, Kolodych S, Hentz A, Ripoll M, Ursuegui S, Nothisen M, Cianférani S, Wagner A

Sci Rep. 2020 May 6;10(1):7691

Ethynylation of Cysteines from Peptides to Proteins in Living Cells.

Tessier R, Nandi RK, Dwyer BG, Abegg D, Sornay C, Ceballos J, Erb S, Cianferani S, Wagner A, Chaubet G, Adibekian A, Waser J

Angew. Chem. Int. Ed. Engl.. 2020 Mar 31;:

Automated linkage of proteins and payloads producing monodisperse conjugates.

Dovgan I, Hentz A, Koniev O, Ehkirch A, Hessmann S, Ursuegui S, Delacroix S, Riomet M, Taran F, Cianférani S, Kolodych S, Wagner A

Chem Sci. 2020 Jan 2;11(5):1210-1215

Long-term efficacy of imatinib mesylate in patients with advanced Tenosynovial Giant Cell Tumor.

Verspoor FGM, Mastboom MJL, Hannink G, Maki RG, Wagner A, Bompas E, Desai J, Italiano A, Seddon BM, van der Graaf WTA, Blay JY, Brahmi M, Eberst L, Stacchiotti S, Mir O, van de Sande MAJ, Gelderblom H, Cassier PA

Sci Rep. 2019 10 10;9(1):14551

Antibody-Oligonucleotide Conjugates as Therapeutic, Imaging, and Detection Agents.

Dovgan I, Koniev O, Kolodych S, Wagner A

Bioconjug. Chem.. 2019 Jul 24;:

Design and evaluation of ionizable peptide amphiphiles for siRNA delivery.

Neuberg P, Wagner A, Remy JS, Kichler A

Int J Pharm. 2019 May 21;:

2nd PSL Chemical Biology Symposium (2019): At the Crossroads of Chemistry and Biology.

Lucchino M, Billet A, Versini A, Bavireddi H, Dasari BD, Debieu S, Colombeau L, Cañeque T, Wagner A, Masson G, Taran F, Karoyan P, Delepierre M, Gaillet C, Houdusse A, Britton S, Schmidt F, Florent JC, Belmont P, Monchaud D, Cossy J, Thomas C, Gautier A, Johannes L, Rodriguez R

Chembiochem. 2019 Feb 25;:

Synthesis and Kinetic evaluation of an azido analogue of methylerythritol phosphate: a Novel Inhibitor of E. coli YgbP/IspD.

Baatarkhuu Z, Chaignon P, Borel F, Ferrer JL, Wagner A, Seemann M

Sci Rep. 2018 Dec 17;8(1):17892

Recent, non-classical, approaches to antibody lysine modification.

Chaubet G, Thoreau F, Wagner A

Drug Discov Today Technol. 2018 Dec;30:21-26

Expedient synthesis of trifunctional oligoethyleneglycol-amine linkers and their use in the preparation of PEG-based branched platforms.

Ursuegui S, Schneider JP, Imbs C, Lauvoisard F, Dudek M, Mosser M, Wagner A

Org. Biomol. Chem.. 2018 Oct 30;:

Co-delivery of anti-PLK-1 siRNA and camptothecin by nanometric polydiacetylenic micelles results in a synergistic cell killing.

Ripoll M, Pierdant M, Neuberg P, Bagnard D, Wagner A, Kichler A, Remy JS

RSC Adv. 2018 Jun 5;8(37):20758-20763

Reduction-rebridging strategy for the preparation of ADPN-based antibody-drug conjugates.

Koniev O, Dovgan I, Renoux B, Ehkirch A, Eberova J, Cianférani S, Kolodych S, Papot S, Wagner A

Medchemcomm. 2018 May 1;9(5):827-830

Inhibition of dengue virus infection by mannoside glycolipid conjugates.

Schaeffer E, Flacher V, Neuberg P, Hoste A, Brulefert A, Fauny JD, Wagner A, Mueller CG

Antiviral Res.. 2018 Apr 6;154:116-123

Arginine-selective bioconjugation with 4-azidophenyl glyoxal: application to the single and dual functionalisation of native antibodies.

Dovgan I, Erb S, Hessmann S, Ursuegui S, Michel C, Muller C, Chaubet G, Cianférani S, Wagner A

Org. Biomol. Chem.. 2018 Feb 21;16(8):1305-1311

Polydiacetylenic nanofibers as new siRNA vehicles for in vitro and in vivo delivery.

Neuberg P, Hamaidi I, Danilin S, Ripoll M, Lindner V, Nothisen M, Wagner A, Kichler A, Massfelder T, Remy JS

Nanoscale. 2018 Jan 25;10(4):1587-1590

Bioorthogonal Click and Release Reaction of Iminosydnones with Cycloalkynes.

Bernard S, Audisio D, Riomet M, Bregant S, Sallustrau A, Plougastel L, Decuypere E, Gabillet S, Kumar RA, Elyian J, Trinh MN, Koniev O, Wagner A, Kolodych S, Taran F

Angew. Chem. Int. Ed. Engl.. 2017 Dec 4;56(49):15612-15616

Structural investigation of cyclo-dioxo maleimide cross-linkers for acid and serum stability.

Tobaldi E, Dovgan I, Mosser M, Becht JM, Wagner A

Org. Biomol. Chem.. 2017 Nov 15;15(44):9305-9310

Development and evaluation of β-galactosidase-sensitive antibody-drug conjugates.

Kolodych S, Michel C, Delacroix S, Koniev O, Ehkirch A, Eberova J, Cianférani S, Renoux B, Krezel W, Poinot P, Muller CD, Papot S, Wagner A

Eur J Med Chem. 2017 Aug;:

An in vivo strategy to counteract post-administration anticoagulant activity of azido-Warfarin.

Ursuegui S, Recher M, Krężel W, Wagner A

Nat Commun. 2017 May;8:15242

Acyl Fluorides: Fast, Efficient, and Versatile Lysine-Based Protein Conjugation via Plug-and-Play Strategy.

Dovgan I, Ursuegui S, Erb S, Michel C, Kolodych S, Cianférani S, Wagner A

Bioconjug. Chem.. 2017 Apr;:

Identification of autoreactive B cells with labeled nucleosomes.

Gies V, Wagner A, Seifert C, Guffroy A, Fauny JD, Knapp AM, Pasquali JL, Martin T, Dumortier H, Korganow AS, Soulas-Sprauel P

Sci Rep. 2017 Apr;7(1):602

pH-Responsive Nanometric Polydiacetylenic Micelles Allow for Efficient Intracellular siRNA Delivery.

Ripoll M, Neuberg P, Kichler A, Tounsi N, Wagner A, Remy JS

ACS Appl Mater Interfaces. 2016 Nov;8(45):30665-30670

Ultrafast Click Chemistry with Fluorosydnones.

Liu H, Audisio D, Plougastel L, Decuypere E, Buisson DA, Koniev O, Kolodych S, Wagner A, Elhabiri M, Krzyczmonik A, Forsback S, Solin O, Gouverneur V, Taran F

Angew. Chem. Int. Ed. Engl.. 2016 Sep;55(39):12073-7

2-(Maleimidomethyl)-1,3-Dioxanes (MD): a Serum-Stable Self-hydrolysable Hydrophilic Alternative to Classical Maleimide Conjugation.

Dovgan I, Kolodych S, Koniev O, Wagner A

Sci Rep. 2016 Aug;6:30835

Palladium-Catalyzed Chemoselective and Biocompatible Functionalization of Cysteine-Containing Molecules at Room Temperature.

Al-Shuaeeb RA, Kolodych S, Koniev O, Delacroix S, Erb S, Nicolaÿ S, Cintrat JC, Brion JD, Cianférani S, Alami M, Wagner A, Messaoudi S

Chemistry. 2016 Aug;22(32):11365-70

From solution to in-cell study of the chemical reactivity of acid sensitive functional groups: a rational approach towards improved cleavable linkers for biospecific endosomal release.

Jacques SA, Leriche G, Mosser M, Nothisen M, Muller CD, Remy JS, Wagner A

Org. Biomol. Chem.. 2016 Jun;14(21):4794-803

Mannoside Glycolipid Conjugates Display Anti-inflammatory Activity by Inhibition of Toll-like Receptor-4 Mediated Cell Activation.

Flacher V, Neuberg P, Point F, Daubeuf F, Muller Q, Sigwalt D, Fauny JD, Remy JS, Frossard N, Wagner A, Mueller CG, Schaeffer E

ACS Chem Biol. 2015 Sep 21.

MAPN: First-in-Class Reagent for Kinetically Resolved Thiol-to-Thiol Conjugation.

Koniev O, Kolodych S, Baatarkhuu Z, Stojko J, Eberova J, Bonnefoy JY, Cianferani S, Van Dorsselaer A, Wagner A

Bioconjug Chem. 2015 Sep 3.

Correction: Developments and recent advancements in the field of endogenous amino acid selective bond forming reactions for bioconjugation.

Koniev O, Wagner A

Chem Soc Rev. 2015 Aug 7;44(15):5743

Photopolymerized micelles of diacetylene amphiphile: physical characterization and cell delivery properties.

Neuberg P, Perino A, Morin-Picardat E, Anton N, Darwich Z, Weltin D, Mely Y, Klymchenko AS, Remy JS, Wagner A

Chem. Commun. (Camb.). 2015 Jul;51(58):11595-8

Spiro Di-orthoester (SpiDo), a Human Plasma Stable Acid-Sensitive Cleavable Linker for Lysosomal Release.

Leriche G, Nothisen M, Baumlin N, Muller CD, Bagnard D, Remy JS, Jacques SA, Wagner A

Bioconjug Chem. 2015 Jul 1.

Developments and recent advancements in the field of endogenous amino acid selective bond forming reactions for bioconjugation.

Koniev O, Wagner A

Chem Soc Rev. 2015 May 22.

Development of models for prediction of the antioxidant activity of derivatives of natural compounds.

Martincic R, Kuzmanovski I, Wagner A, Novic M

Anal Chim Acta. 2015 Apr 8;868:23-35

Discovery of Potent Inhibitors of Schistosoma mansoni NAD(+) Catabolizing Enzyme.

Jacques SA, Kuhn I, Koniev O, Schuber F, Lund FE, Wagner A, Muller-Steffner H, Kellenberger E

J Med Chem. 2015 Apr 23;58(8):3582-92

CBTF: new amine-to-thiol coupling reagent for preparation of antibody conjugates with increased plasma stability.

Kolodych S, Koniev O, Baatarkhuu Z, Bonnefoy JY, Debaene F, Cianferani S, Van Dorsselaer A, Wagner A

Bioconjug Chem. 2015 Feb 18;26(2):197-200

Bio-specific and bio-orthogonal chemistries to switch-off the quencher of a FRET-based fluorescent probe: application to living-cell biothiol imaging.

Egloff C, Jacques SA, Nothisen M, Weltin D, Calligaro C, Mosser M, Remy JS, Wagner A

Chem Commun (Camb). 2014 Sep 11;50(70):10049-51

4-Halogeno-sydnones for fast strain promoted cycloaddition with bicyclo-[6.1.0]-nonyne.

Plougastel L, Koniev O, Specklin S, Decuypere E, Creminon C, Buisson DA, Wagner A, Kolodych S, Taran F

Chem Commun (Camb). 2014 Aug 25;50(66):9376-8

Developments in the field of bioorthogonal bond forming reactions-past and present trends.

King M, Wagner A

Bioconjug Chem. 2014 May 21;25(5):825-39

Selective irreversible chemical tagging of cysteine with 3-arylpropiolonitriles.

Koniev O, Leriche G, Nothisen M, Remy JS, Strub JM, Schaeffer-Reiss C, Van Dorsselaer A, Baati R, Wagner A

Bioconjug Chem. 2014 Feb 19;25(2):202-6

Dynamic micelles of mannoside glycolipids are more efficient than polymers for inhibiting HIV-1 trans-infection.

Schaeffer E, Dehuyser L, Sigwalt D, Flacher V, Bernacchi S, Chaloin O, Remy JS, Mueller CG, Baati R, Wagner A

Bioconjug Chem. 2013 Nov 20;24(11):1813-23

A new series of Cs+, K+ and Na+ chelators: Synthesis, kinetics, thermodynamics and modeling.

Korovitch A, Le Roux A, Barbault F, Hemadi M, Ha-Duong NT, Lion C, Wagner A, Chahine JME

Inorg Chim Acta. 2013 Jan 1;394:45-57.

First steps towards conformationally selective artificial lectins: the chair-boat discrimination by molecularly imprinted polymers.

de Talance VL, Massinon O, Baati R, Wagner A, Vincent SP

Chem Commun (Camb). 2012 Nov 7;48(86):10684-6

Synthesis of novel mannoside glycolipid conjugates for inhibition of HIV-1 trans-infection.

Dehuyser L, Schaeffer E, Chaloin O, Mueller CG, Baati R, Wagner A

Bioconjug Chem. 2012 Sep 19;23(9):1731-9

Towards a KCC2 blocker pharmacophore model.

Lebon F, Pegurier C, Ledecq M, Mathieu B, Bosman N, Frycia A, Lengele S, Dhurke K, Kanduluru AK, Meunier S, Wagner A, Wolff C, Provins L

Bioorg Med Chem Lett. 2012 Jun 15;22(12):3978-82

A FRET-based probe with a chemically deactivatable quencher.

Leriche G, Budin G, Darwich Z, Weltin D, Mely Y, Klymchenko AS, Wagner A

Chem Commun (Camb). 2012 Mar 28;48(26):3224-6

Capillary electrophoresis-inductively coupled plasma-mass spectrometry hyphenation for the determination at the nanogram scale of metal affinities and binding constants of phosphorylated ligands.

Varenne F, Bourdillon M, Meyer M, Lin Y, Brellier M, Baati R, Charbonniere LJ, Wagner A, Doris E, Taran F, Hagege A

J Chromatogr A. 2012 Mar 16;1229:280-7

Cleavable linkers in chemical biology.

Leriche G, Chisholm L, Wagner A

Bioorg Med Chem. 2012 Jan 15;20(2):571-82

Mild chemo-selective hydration of terminal alkynes catalysed by AgSbF6.

Thuong MB, Mann A, Wagner A

Chem Commun (Camb). 2012 Jan 11;48(3):434-6

Trimethoxyarene as a Highly Ionizable Tag for Reaction Analysis by Atmospheric Pressure Photoionization Mass Spectrometry (APPI/MS): Exploration of Heterocyclic Synthesis.

Mathieu BTT, Catala C, Colas C, Schaeffer C, Van Dorsselaer A, Mann A, Wagner A

. 2012 Jan;1:85-92.

Design and synthesis of new antioxidants predicted by the model developed on a set of pulvinic acid derivatives.

Le Roux A, Kuzmanovski I, Habrant D, Meunier S, Bischoff P, Nadal B, Thetiot-Laurent SA, Le Gall T, Wagner A, Novic M

J Chem Inf Model. 2011 Dec 27;51(12):3050-9

Cationic polydiacetylene micelles for gene delivery.

Morin E, Nothisen M, Wagner A, Remy JS

Bioconjug Chem. 2011 Oct 19;22(10):1916-23

Self-assembled nanotubes and helical tapes from diacetylene nonionic amphiphiles. Structural studies before and after polymerization.

Perino A, Schmutz M, Meunier S, Mesini PJ, Wagner A

Langmuir. 2011 Oct 4;27(19):12149-55

Stereoselective Addition of Grignard Reagents to New P-Chirogenic N-Phosphinoylbenzaldimines: Effect of the Phosphorus Substituents on the Stereoselectivity.

Francesco IN, Egloff C, Wagner A, Colobert F

. 2011 Jul;20-21:4037-45.

Cationic cyclization of 2-alkenyl-1,3-dithiolanes: diastereoselective synthesis of trans-decalins.

Goncalves S, Santoro S, Nicolas M, Wagner A, Maillos P, Himo F, Baati R

J Org Chem. 2011 May 6;76(9):3274-85

First efficient uncharged reactivators for the dephosphylation of poisoned human acetylcholinesterase.

Mercey G, Verdelet T, Saint-Andre G, Gillon E, Wagner A, Baati R, Jean L, Nachon F, Renard PY

Chem Commun (Camb). 2011 May 14;47(18):5295-7

A REPRESENTATION TO APPLY USUAL DATA MINING TECHNIQUES TO CHEMICAL REACTIONS - ILLUSTRATION ON THE RATE CONSTANT OF S(N)2 REACTIONS IN WATER.

Hoonakker F, Lachiche N, Varnek A, Wagner A

. 2011 Apr;20(2):253-70.

Programmed Dispersions of MWNTs in Aqueous Media by Coating with Photopolymerizable Synthetic Amphiphiles.

Thauvin C, Perino A, Contal E, Morin E, Schutz P, Meunier S, Wagner A

. 2011 Apr 21;115(15):7319-22.

Synthesis and radioprotective properties of pulvinic acid derivatives.

Le Roux A, Meunier S, Le Gall T, Denis JM, Bischoff P, Wagner A

ChemMedChem. 2011 Mar 7;6(3):561-9

Structure and Behavior of Polydiacetylene-Based Micelles.

Perino A, Klymchenko A, Morere A, Contal E, Rameau A, Guenet JM, Mely Y, Wagner A

. 2011 Jan 18;212(2):111-7.

Tailoring drug release profile of low-molecular-weight hydrogels by supramolecular co-assembly and thiol-ene orthogonal coupling.

Diaz DD, Morin E, Schon EM, Budin G, Wagner A, Remy JS

. 2011;21(3):641-4.

Redefining the TGR5 triterpenoid binding pocket at the C-3 position.

Genet C, Schmidt C, Strehle A, Schoonjans K, Auwerx J, Saladin R, Wagner A

ChemMedChem. 2010 Dec 3;5(12):1983-8.

Structure-Reactivity Relationship Studies for Guanidine-Organocatalyzed Direct Intramolecular Aldolization of Ketoaldehydes.

Ghobril C, Hammar P, Kodepelly S, Spiess B, Wagner A, Himo F, Baati R

Chemcatchem. 2010 Dec;2(12):1573-81.

Nondenaturing chemical proteomics for protein complex isolation and identification.

Budin G, Moune-Dimala M, Leriche G, Saliou JM, Papillon J, Sanglier-Cianferani S, Van Dorsselaer A, Lamour V, Brino L, Wagner A

Chembiochem. 2010 Nov 22;11(17):2359-61.

Synthesis and antioxidant properties of pulvinic acids analogues.

Nadal B, Thetiot-Laurent SA, Pin S, Renault JP, Cressier D, Rima G, Le Roux A, Meunier S, Wagner A, Lion C, Le Gall T

Bioorg Med Chem. 2010 Nov 15;18(22):7931-9

Fine-tuning the morphology of self-assembled nanostructures of propargyl ammonium-based amphiphiles.

Morin E, Guenet JM, Diaz DD, Remy JS, Wagner A

J Phys Chem B. 2010 Oct 7;114(39):12495-500.

An efficient one-pot four-step domino reaction for the synthesis of C2-substituted 3-methylcyclohex-2-enones.

Goncalves S, Maillos P, Nicolas M, Wagner A, Baati R

Tetrahedron. 2010 Sep 25;66(39):7856-60.

Diastereoselective formal total synthesis of (+/-)-triptolide via a novel cationic cyclization of 2-alkenyl-1,3-dithiolane.

Goncalves S, Hellier P, Nicolas M, Wagner A, Baati R

Chem Commun (Camb). 2010 Aug 21;46(31):5778-80

A Practical and Efficient Total Synthesis of Potent Insulinotropic (2S,3R,4S)-4-Hydroxyisoleucine through a Chiral N-Protected gamma-Keto-alpha-aminoester

Marin SD, Catala C, Kumar SR, Valleix A, Wagner A, Mioskowski C

Eur J Org Chem. 2010 Jul;21:3985-9

Theoretical mechanistic study of the TBD-catalyzed intramolecular aldol reaction of ketoaldehydes.

Hammar P, Ghobril C, Antheaume C, Wagner A, Baati R, Himo F

J Org Chem. 2010 Jul 16;75(14):4728-36.

Highly chemo- and stereoselective glycosidation of permethacrylated O-glycosyl trichloroacetimidate reagents promoted by TMSNTf2

Zandanel C, Dehuyser L, Wagner A, Baati R

Tetrahedron. 2010 May 1;66(18):3365-9

Chemoselective addition of in situ prepared lithium alkynyl borates to aldehydes: a practical and transition metal free approach toward the synthesis of propargylic alcohols

Francesco IN, Renier A, Wagner A, Colobert F

Tetrahedron Lett. 2010 Mar 10;51(10):1386-9

Structure-activity relationship study of betulinic acid, a novel and selective TGR5 agonist, and its synthetic derivatives: potential impact in diabetes.

Genet C, Strehle A, Schmidt C, Boudjelal G, Lobstein A, Schoonjans K, Souchet M, Auwerx J, Saladin R, Wagner A

J Med Chem. 2010 Jan 14;53(1):178-90.

Sequential Hiyama Coupling/Narasaka Acylation Reaction of (E)-1,2-Disilylethene: Rapid Assembly of alpha,beta-Unsaturated Carbonyl Motifs

Thiot C, Mioskowski C, Wagner A

Eur J Org Chem. 2009 Jul;19:3219-27

Novel chiral derivatizing isothiocyanate-based agent for the enantiomeric excess determination of amines.

Sabot C, Mosser M, Antheaume C, Mioskowski C, Baati R, Wagner A

Chem Commun (Camb). 2009 Jun 21;(23):3410-2

Semi-covalent surface molecular imprinting of polymers by one-stage mini-emulsion polymerization: glucopyranoside as a model analyte.

Curcio P, Zandanel C, Wagner A, Mioskowski C, Baati R

Macromol Biosci. 2009 Jun 11;9(6):596-604.

Highly stereoselective synthesis of (Z,E)-1-halo-1,3-dienol esters via rearrangement of Fischer chromium chloro-carbenes using microwave irradiation.

Kashinath D, Mioskowski C, Falck JR, Goli M, Meunier S, Baati R, Wagner A

Org Biomol Chem. 2009 May 7;7(9):1771-4

A one-pot synthesis of (E)-disubstituted alkenes by a bimetallic [Rh-Pd]-catalyzed hydrosilylation/hiyama cross-coupling sequence.

Thiot C, Schmutz M, Wagner A, Mioskowski C

Chemistry. 2007;13(32):8971-8.

Pd(II)-catalyzed cascade Wacker-Heck reaction: chemoselective coupling of two electron-deficient reactants.

Silva F, Reiter M, Mills-Webb R, Sawicki M, Klar D, Bensel N, Wagner A, Gouverneur V

J Org Chem. 2006 Oct 27;71(22):8390-4.

Short and efficient preparations of isoxazole-3-carboxylic acid and imino-oxopentanoic acid potent precursors of 4-hydroxyisoleucine.

Becht JM, Marin SD, Maruani M, Wagner A, Mioskowski C

Tetrahedron. 2006 May 1;62(18):4430-4.

Polyionic gels: efficient heterogeneous media for metal scavenging and catalysis.

Thiot C, Schmutz M, Wagner A, Mioskowski C

Angew Chem Int Ed Engl. 2006 Apr 28;45(18):2868-71.

Unprecedented, fully recyclable, solid-supported reagent for the kinetic resolution of racemic amines through enantioselective N-acetylation.

Arseniyadis S, Subhash PV, Valleix A, Wagner A, Mioskowski C

Chem Commun (Camb). 2005 Jul 14;(26):3310-2

Tuning the enantioselective N-acetylation of racemic amines: a spectacular salt effect.

Arseniyadis S, Subhash PV, Valleix A, Mathew SP, Blackmond DG, Wagner A, Mioskowski C

J Am Chem Soc. 2005 May 4;127(17):6138-9.

Dr WAGNER Alain

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