Pr HEURTAULT Béatrice

Fiche personne

Coordonnées

CRBS
1 rue Eugène Boeckel
67084 STRASBOURG Cedex

Territoire

Alsace

Statut

Enseignant-Chercheur

Affiliation

Biomatériaux et bioingénierie - Inserm UMR_S 1121/EMR 7003 (UMR_S U1121)

Université de Strasbourg (Unistra)

Centre de recherche en biomédecine de Strasbourg (CRBS)

Équipes/plateformes

UMR_S 1121 - Equipe "Implants ORL et pédiatriques"

UMR_S 1121 - Equipe "Biomatérieux et inflammation"

Publications

N-Heterocyclic carbene platinum complexes encapsulated in lipid particles: a novel strategy to target cancer cells and cancer stem cells in glioblastoma.

Fernandez de Larrinoa P, Kichler A, Dontenwill M, Herold-Mende C, Fournel S, Frisch B, Bellemin-Laponnaz S, Heurtault B

RSC Med Chem. 2025 06 2;:

NOD1 Agonist Induces Proliferation and Plasma Cell Differentiation of Mouse B Cells Especially CD23 B Cells.

Seguin C, Seif M, Jacoberger-Foissac C, Gentine P, Wantz M, Frisch B, Heurtault B, Fournel S

Immunol Invest. 2024 11 19;:1-15

Triplet-Triplet Annihilation Upconversion Based Photolysis: Applications in Photopharmacology.

Klimezak M, Chaud J, Brion A, Bolze F, Frisch B, Heurtault B, Kichler A, Specht A

Adv Healthc Mater. 2024 04 13;:e2400354

The antibacterial properties of branched peptides based on poly(l-arginine): In vitro antibacterial evaluation and molecular dynamic simulations.

Eloïse L, Petit L, Nominé Y, Heurtault B, Ben Hadj Kaddour I, Senger B, Rodon Fores J, Vrana NE, Barbault F, Lavalle P

Eur J Med Chem. 2024 02 10;268:116224

Fluorescent bioinspired albumin/polydopamine nanoparticles and their interactions with cells.

Equy E, Hirtzel J, Hellé S, Heurtault B, Mathieu E, Rabineau M, Ball V, Ploux L

Beilstein J Nanotechnol. 2023 12 22;14:1208-1224

Preclinical evaluation of implantable materials: conventional approaches, new models and future directions.

Frisch E, Clavier L, Belhamdi A, Vrana NE, Lavalle P, Frisch B, Heurtault B, Gribova V

Front Bioeng Biotechnol. 2023 07 27;11:1193204

Photoactivatable Liposomes for Blue to Deep Red Light-Activated Surface Drug Release: Application to Controlled Delivery of the Antitumoral Drug Melphalan.

Brion A, Chaud J, Klimezak M, Bolze F, Ohlmann L, Léonard J, Chassaing S, Frisch B, Kichler A, Heurtault B, Specht A

Bioconjug Chem. 2023 07 1;:

Triphenylphosphonium-functionalized N-heterocyclic carbene platinum complexes [(NHC-TPP)Pt] induce cell death of human glioblastoma cancer stem cells.

Fernandez de Larrinoa P, Parmentier J, Kichler A, Achard T, Dontenwill M, Herold-Mende C, Fournel S, Frisch B, Heurtault B, Bellemin-Laponnaz S

Int J Pharm. 2023 05 25;:123071

Click Chemistry for Liposome Surface Modification.

Spanedda MV, De Giorgi M, Heurtault B, Kichler A, Bourel-Bonnet L, Frisch B

Methods Mol Biol. 2023 ;2622:173-189

Evaluation of the Cytotoxicity of Cationic Polymers on Glioblastoma Cancer Stem Cells.

McCartin C, Blumberger J, Dussouillez C, Fernandez de Larrinoa P, Dontenwill M, Herold-Mende C, Lavalle P, Heurtault B, Bellemin-Laponnaz S, Fournel S, Kichler A

J Funct Biomater. 2022 12 28;14(1):

Formulation and Rheological Evaluation of Liposomes-Loaded Carbopol Hydrogels Based on Thermal Waters.

Mokdad R, Aouabed A, Ball V, Si Youcef FF, Nasrallah N, Heurtault B, HadjSadok A

Drug Dev Ind Pharm. 2022 11 24;:1-29

Red Light-Responsive Upconverting Nanoparticles for Quantitative and Controlled Release of a Coumarin-Based Prodrug.

Brion A, Chaud J, Léonard J, Bolze F, Chassaing S, Frisch B, Heurtault B, Kichler A, Specht A

Adv Healthc Mater. 2022 10 12;:e2201474

Impact of anti-PDGFRα antibody surface functionalization on LNC uptake by oligodendrocyte progenitor cells.

Labrak Y, Heurtault B, Frisch B, Saulnier P, Lepeltier E, Miron VE, Muccioli GG, des Rieux A

Int J Pharm. 2022 Feb 26;:121623

Anti-inflammatory effects of free and liposome-encapsulated natural Algerian thermal water in RAW 264.7 macrophages.

Mokdad R, Seguin C, Fournel S, Frisch B, Heurtault B, Hadjsadok A

Int J Pharm. 2022 Jan 7;:121452

Development and Characterization of Layer-by-Layer Coated Liposomes with Poly(L-Lysine) and Poly(L-Glutamic Acid) to Increase their Resistance in Biological Media.

Hermal F, Frisch B, Specht A, Bourel-Bonnet L, Heurtault B

Int J Pharm. 2020 Jun 24;:119568

Liposomes as tunable platform to decipher the antitumor immune response triggered by TLR and NLR agonists.

Jacoberger-Foissac C, Saliba H, Wantz M, Seguin C, Flacher V, Frisch B, Heurtault B, Fournel S

Eur J Pharm Biopharm. 2020 May 29;:

Optimization of peptide-based cancer vaccine compositions, by sequential screening, using versatile liposomal platform.

Jacoberger-Foissac C, Saliba H, Seguin C, Brion A, Kakhi Z, Frisch B, Fournel S, Heurtault B

Int J Pharm. 2019 Mar 14;:

Enhancing tumor specific immune responses by transcutaneous vaccination.

Saliba H, Heurtault B, Bouharoun-Tayoun H, Flacher V, Frisch B, Fournel S, Chamat S

Expert Rev Vaccines. 2017 Sep;:

Solubilization of α-galactosylceramide in aqueous medium: impact on Natural Killer T cell activation and antitumor responses.

Macho-Fernandez E, Chekkat N, Ehret C, Thomann JS, De Giorgi M, Spanedda MV, Bourel-Bonnet L, Betbeder D, Heurtault B, Faveeuw C, Fournel S, Frisch B, Trottein F

Int J Pharm. 2017 Jul;:

Exogenous Activation of Invariant Natural Killer T Cells by α-Galactosylceramide Reduces Pneumococcal Outgrowth and Dissemination Postinfluenza.

Barthelemy A, Ivanov S, Hassane M, Fontaine J, Heurtault B, Frisch B, Faveeuw C, Paget C, Trottein F

MBio. 2016 Nov;7(6):

Liposomal constructs for antitumoral vaccination by the nasal route.

Kakhi Z, Frisch B, Heurtault B, Pons F

Biochimie. 2016 Nov;130:14-22

Airway administration of a highly versatile peptide-based liposomal construct for local and distant antitumoral vaccination.

Kakhi Z, Frisch B, Bourel-Bonnet L, Hemmerlé J, Pons F, Heurtault B

Int J Pharm. 2015 Dec;496(2):1047-56

Smart tools and orthogonal click-like reactions onto small unilamellar vesicles: Additional molecular data.

Vittoria Spanedda M, Salome C, Hilbold B, Berner E, Heurtault B, Fournel S, Frisch B, Bourel-Bonnet L

Data Brief. 2015 Aug 28;5:145-54

Smart tools and orthogonal click-like reactions onto small unilamellar vesicles.

Salomé C, Spanedda MV, Hilbold B, Berner E, Heurtault B, Fournel S, Frisch B, Bourel-Bonnet L

Chem. Phys. Lipids. 2015 May;188:27-36

Extensive study of human insulin immunoassays: promises and pitfalls for insulin analogue detection and quantification.

Heurtault B, Reix N, Meyer N, Gasser F, Wendling MJ, Ratomponirina C, Jeandidier N, Sapin R, Agin A

Clin Chem Lab Med. 2014 Mar;52(3):355-62

Thyroid-stimulating hormone and free thyroxine on the ADVIA Centaur immunoassay system: a multicenter assessment of analytical performance.

Reix N, Massart C, d'Herbomez M, Gasser F, Heurtault B, Agin A

Clin Biochem. 2013 Sep;46(13-14):1305-8

Glycemic management of diabetes by insulin therapy.

Reix N, Sigrist S, Heurtault B, Agin A, Moreau F, Pinget M, Jeandidier N

Minerva Endocrinol. 2013 Mar;38(1):29-46.

Should functional sensitivity of a new thyroid stimulating hormone immunoassay be monitored routinely? The ADVIA Centaur TSH3-UL assay experience.

Reix N, Massart C, Gasser F, Heurtault B, Agin A

Clin Biochem. 2012 Oct;45(15):1260-2

Novel glycolipid TLR2 ligands of the type Pam2Cys-alpha-Gal: synthesis and biological properties.

Thomann JS, Monneaux F, Creusat G, Spanedda MV, Heurtault B, Habermacher C, Schuber F, Bourel-Bonnet L, Frisch B

Eur J Med Chem. 2012 May;51:174-83

Activation of invariant Natural Killer T lymphocytes in response to the alpha-galactosylceramide analogue KRN7000 encapsulated in PLGA-based nanoparticles and microparticles.

Macho Fernandez E, Chang J, Fontaine J, Bialecki E, Rodriguez F, Werkmeister E, Krieger V, Ehret C, Heurtault B, Fournel S, Frisch B, Betbeder D, Faveeuw C, Trottein F

Int J Pharm. 2012 Feb 14;423(1):45-54

Antitumor activity of liposomal ErbB2/HER2 epitope peptide-based vaccine constructs incorporating TLR agonists and mannose receptor targeting.

Thomann JS, Heurtault B, Weidner S, Braye M, Beyrath J, Fournel S, Schuber F, Frisch B

Biomaterials. 2011 Jul;32(20):4574-83

Liposomes as delivery systems for nasal vaccination: strategies and outcomes.

Heurtault B, Frisch B, Pons F

Expert Opin Drug Deliv. 2010 Jul;7(7):829-44.

Novel powerful water-soluble lipid immunoadjuvants inducing mouse dendritic cell maturation and B cell proliferation using TLR2 pathway.

Spanedda MV, Heurtault B, Weidner S, Baehr C, Boeglin E, Beyrath J, Milosevic S, Bourel-Bonnet L, Fournel S, Frisch B

Bioorg Med Chem Lett. 2010 Mar 15;20(6):1869-72

Consequences of isostructural main-chain modifications for the design of antimicrobial foldamers: helical mimics of host-defense peptides based on a heterogeneous amide/urea backbone.

Claudon P, Violette A, Lamour K, Decossas M, Fournel S, Heurtault B, Godet J, Mely Y, Jamart-Gregoire B, Averlant-Petit MC, Briand JP, Duportail G, Monteil H, Guichard G

Angew Chem Int Ed Engl. 2010;49(2):333-6.