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Bone cells modulate colonization and biofilm formation on bone and titanium.

Varin-Simon J, Guillaume C, Dghoughi Y, Siboni R, Velard F, Gangloff SC, Colin M, Reffuveille F

Biofilm. 2026 12;12:100404

In vitro characterization of osteoblasts from craniofacial fibrous dysplasia of bone and their impact on bone homeostasis.

Sergheraert J, Dumortier C, Guillaume C, Laurence S, Bornert F, Gangloff SC, Mauprivez C, Velard F

Orphanet J Rare Dis. 2026 02 24;:

Toward an improved in vitro model of prosthetic joint infection for biofilm characterization.

Dghoughi Y, Varin-Simon J, Gangloff SC, Colin M, Reffuveille F

Biofilm. 2025 12;10:100325

Optimisation and Validation of an Induced Membrane Technique Model to Assess Bone Regeneration in Rats.

Siboni R, Sergheraert J, Thoraval L, Guillaume C, Gangloff SC, Ohl X, Braux J, Velard F

J Tissue Eng Regen Med. 2025 04 21;2025:7357277

D-enantiomeric antibiofilm peptides effective against anaerobic biofilm.

Varin-Simon J, Haney EF, Colin M, Velard F, Gangloff SC, Hancock REW, Reffuveille F

Microbiol Spectr. 2025 03 25;:e0252324

CFTR mutation is associated with bone differentiation abnormalities in cystic fibrosis.

Dumortier C, Frauenpreis A, Hoarau A, Ryan AL, Gangloff SC, Danopoulos S, Velard F, Al Alam D

J Cyst Fibros. 2025 01 11;:

Characteristics of hospital pharmacist interventions and their clinical, economic and organizational impacts: a five-year observational study on the French National Observatory.

Clarenne J, Mongaret C, Vermorel C, Bosson JL, Gangloff SC, Lambert-Lacroix S, Bedouch P

Int J Clin Pharm. 2024 12 13;:

Cutibacterium acnes strains associated with bone prosthesis infections cannot evade the host immune system.

Thoraval L, Tang-Fichaux M, Guillaume C, Varin-Simon J, Dumortier C, Sergheraert J, Lamret F, Bonhomme M, Laurent F, Josse J, Gangloff SC, Mongaret C, Reffuveille F, Velard F

Front Immunol. 2024 11 27;15:1468709

Cutibacterium acnes biofilm formation is influenced by bone microenvironment, implant surfaces and bacterial internalization.

Varin-Simon J, Colin M, Velard F, Tang-Fichaux M, Ohl X, Mongaret C, Gangloff SC, Reffuveille F

BMC Microbiol. 2024 07 20;24(1):270

Antifungal and Coagulation Properties of a Copper (I) Oxide Nanopowder Produced by Out-of-Phase Pulsed Sonoelectrochemistry.

Mancier V, Fattoum S, Haguet H, Laloy J, Maillet C, Gangloff SC, Chopart JP

Antibiotics (Basel). 2024 03 21;13(3):

UVC Box: An Effective Way to Quickly Decontaminate Healthcare Facilities' Wheelchairs.

Adam C, Colin M, Stock R, Weiss L, Gangloff SC

Life (Basel). 2024 02 16;14(2):

Approaching prosthesis infection environment: Development of an innovative biofilm model.

Lamret F, Lemaire A, Lagoutte M, Varin-Simon J, Abraham L, Colin M, Braux J, Velard F, Gangloff SC, Reffuveille F

Biofilm. 2023 12;5:100120

The acute inflammatory response to copper(II)-doped biphasic calcium phosphates.

Thoraval L, Thiébault E, Siboni R, Moniot A, Guillaume C, Jacobs A, Nedelec JM, Renaudin G, Descamps S, Valfort O, Gangloff SC, Braux J, Marchat D, Velard F

Mater Today Bio. 2023 12;23:100814

Cytocompatibility of titanium and poly(etheretherketone) surfaces after O2 non-thermal plasma sterilization.

Maillet C, Klein FM, Le Bras F, Velard F, Guillaume C, Gangloff SC, Gelle MP

PLoS One. 2023 08 30;18(8):e0290820

Behavior on Artificial Surfaces Mimicking Bone Environment.

Lemaire A, Varin-Simon J, Lamret F, Dubus M, Kerdjoudj H, Velard F, Gangloff SC, Reffuveille F

Pathogens. 2023 02 28;12(3):

Effects of Ageing in Disinfectant Solution on the Corrosion Resistance and Antimicrobial Behavior of Copper Alloys.

Lazar FS, Colin M, Carré G, Bachelard N, Chopart JP, Gangloff SC

Molecules. 2023 01 18;28(3):

Human Osteoblast-Conditioned Media Can Influence Biofilm Formation.

Lamret F, Varin-Simon J, Six M, Thoraval L, Chevrier J, Adam C, Guillaume C, Velard F, Gangloff SC, Reffuveille F

Int J Mol Sci. 2022 11 19;23(22):

Inhibition of Recruitment and Activation of Neutrophils by Pyridazinone-Scaffold-Based Compounds.

Moniot A, Braux J, Siboni R, Guillaume C, Audonnet S, Allart-Simon I, Sapi J, Tirouvanziam R, Gérard S, Gangloff SC, Velard F

Int J Mol Sci. 2022 06 29;23(13):

Decellularization of Wharton's Jelly Increases Its Bioactivity and Antibacterial Properties.

Dubus M, Scomazzon L, Chevrier J, Montanede A, Baldit A, Terryn C, Quilès F, Thomachot-Schneider C, Gangloff SC, Bouland N, Gindraux F, Rammal H, Mauprivez C, Kerdjoudj H

Front Bioeng Biotechnol. 2022 ;10:828424

Pyridazinone Derivatives Limit Osteosarcoma-Cells Growth In Vitro and In Vivo.

Moniot A, Braux J, Bour C, Guillaume C, Lamret F, Allart-Simon I, Audonnet S, Renault S, Rédini F, Laronze-Cochard M, Sapi J, Gangloff SC, Gérard S, Velard F

Cancers (Basel). 2021 Nov 28;13(23):

Bone marrow mesenchymal stem cells offer an immune-privileged niche to Cutibacterium acnes in case of implant-associated osteomyelitis.

Dubus M, Varin J, Papa S, Chevrier J, Quilès F, Francius G, Audonnet S, Mauprivez C, Gangloff SC, Siboni R, Ohl X, Reffuveille F, Kerdjoudj H

Acta Biomater. 2021 Oct 19;:

Synergy between Indoloquinolines and Ciprofloxacin: An Antibiofilm Strategy against .

Charpentier E, Doudet L, Allart-Simon I, Colin M, Gangloff SC, Gérard S, Reffuveille F

Antibiotics (Basel). 2021 Oct 4;10(10):

Comparison of Two Biofilm Models.

Varin-Simon J, Lamret F, Colin M, Gangloff SC, Mongaret C, Reffuveille F

Microorganisms. 2021 Sep 26;9(10):

Interaction of implant infection-related commensal bacteria with mesenchymal stem cells: A comparison between Cutibacterium acnes and Staphylococcus aureus.

El-Mahdy TS, Mongaret C, Varin-Simon J, Lamret F, Vernet-Garnier V, Rammal H, Mauprivez C, Kerdjoudj H, Gangloff SC, Reffuveille F

FEMS Microbiol Lett. 2021 Feb 13;:

Strain-Dependent Biofilm Formation in Bone-Like Environment.

Lamret F, Varin-Simon J, Velard F, Terryn C, Mongaret C, Colin M, Gangloff SC, Reffuveille F

Front Microbiol. 2021 ;12:714994

Osteoclastogenesis and sphingosine-1-phosphate secretion from human osteoclast precursor monocytes are modulated by the cystic fibrosis transmembrane conductance regulator.

Jourdain ML, Sergheraert J, Braux J, Guillaume C, Gangloff SC, Hubert D, Velard F, Jacquot J

Biochim Biophys Acta Mol Basis Dis. 2020 Nov 11;:166010

Biofilm Study during Bone Cells Interaction.

Mongaret C, Varin-Simon J, Lamret F, El-Mahdy TS, Brasme L, Vernet-Garnier V, Gangloff SC, Ohl X, Reffuveille F

Microorganisms. 2020 Sep 12;8(9):

Antibiotic Tolerance of Biofilm in Periprosthetic Joint Infections and Antibiofilm Strategies.

Lamret F, Colin M, Mongaret C, Gangloff SC, Reffuveille F

Antibiotics (Basel). 2020 Aug 27;9(9):

Mechanobiologically induced bone-like nodules: Matrix characterization from micro to nanoscale.

Rammal H, Dubus M, Bercu NB, Mathieu E, Terryn C, Molinari M, Gangloff SC, Nassif N, Mauprivez C, Quilès F, Kerdjoudj H

Nanomedicine. 2020 Jun 29;:102256

Abundant Extractable Metabolites from Temperate Tree Barks: The Specific Antimicrobial Activity of Extracts.

Abedini A, Colin M, Hubert J, Charpentier E, Angelis A, Bounasri H, Bertaux B, Kotland A, Reffuveille F, Nuzillard JM, Renault JH, Gangloff SC

Antibiotics (Basel). 2020 Mar 4;9(3):

Infection of Human Dental Pulp Stromal Cells by : Shedding Light on Bacteria Pathogenicity and Pulp Inflammation.

Maisonneuve E, Chevrier J, Dubus M, Varin J, Sergheraert J, Gangloff SC, Reffuveille F, Mauprivez C, Kerdjoudj H

. 2020 ;8:785

Interaction of Cutibacterium acnes with human bone marrow derived mesenchymal stem cells: a step toward understanding bone implant- associated infection development.

Dubus M, Varin J, Papa S, Rammal H, Chevrier J, Maisonneuve E, Mauprivez C, Mongaret C, Gangloff SC, Reffuveille F, Kerdjoudj H

Acta Biomater. 2019 Dec 24;:

Specific antibacterial activity of copper alloy touch surfaces in five long-term care facilities for older adults.

Colin M, Charpentier E, Klingelschmitt F, Bontemps C, De Champs C, Reffuveille F, Gangloff SC

J. Hosp. Infect.. 2019 Dec 3;:

Triterpenes from Salvia argentea var. aurasiaca and their antibacterial and cytotoxic activities.

Bechkri S, Magid AA, Voutquenne-Nazabadioko L, Djemaa B, Kabouche A, Lehbili M, Lakhal H, Abedini A, Gangloff SC, Morjani H, Kabouche Z

Fitoterapia. 2019 Aug 8;:104296

Cationic antimicrobial peptides and periodontal physiopathology: A systematic review.

Jourdain ML, Velard F, Pierrard L, Sergheraert J, Gangloff SC, Braux J

J. Periodont. Res.. 2019 Jun 19;:

Boosting mesenchymal stem cells regenerative activities on biopolymers-calcium phosphate functionalized collagen membrane.

Dubus M, Rammal H, Alem H, Bercu NB, Royaud I, Quilès F, Boulmedais F, Gangloff SC, Mauprivez C, Kerdjoudj H

Colloids Surf B Biointerfaces. 2019 Jun 15;181:671-679

Cowries derived aragonite as raw biomaterials for bone regenerative medicine.

Akilal N, Lemaire F, Bercu NB, Sayen S, Gangloff SC, Khelfaoui Y, Rammal H, Kerdjoudj H

Mater Sci Eng C Mater Biol Appl. 2019 Jan 1;94:894-900

Osteoinductive Material to Fine-Tune Paracrine Crosstalk of Mesenchymal Stem Cells With Endothelial Cells and Osteoblasts.

Rammal H, Entz L, Dubus M, Moniot A, Bercu NB, Sergheraert J, Gangloff SC, Mauprivez C, Kerdjoudj H

Front Bioeng Biotechnol. 2019 ;7:256

Copper Alloy Touch Surfaces in Healthcare Facilities: An Effective Solution to Prevent Bacterial Spreading.

Colin M, Klingelschmitt F, Charpentier E, Josse J, Kanagaratnam L, De Champs C, Gangloff SC

Materials (Basel). 2018 Dec 6;11(12):

Combining Calcium Phosphates with Polysaccharides: A Bone-Inspired Material Modulating Monocyte/Macrophage Early Inflammatory Response.

Rammal H, Bour C, Dubus M, Entz L, Aubert L, Gangloff SC, Audonnet S, Bercu NB, Boulmedais F, Mauprivez C, Kerdjoudj H

Int J Mol Sci. 2018 Nov 3;19(11):

Predictive factors for clinically significant pharmacist interventions at hospital admission.

Mongaret C, Quillet P, Vo TH, Aubert L, Fourgeaud M, Michelet-Huot E, Bonnet M, Bedouch P, Slimano F, Gangloff SC, Drame M, Hettler D

Medicine (Baltimore). 2018 03;97(9):e9865

Chemical constituents of Genista numidica Spach aerial parts and their antimicrobial, antioxidant and antityrosinase activities.

Boutaghane N, Alabdul Magid A, Abedini A, Cafolla A, Djeghim H, Gangloff SC, Voutquenne-Nazabadioko L, Kabouche Z

Nat. Prod. Res.. 2018 Feb 15;:1-7

Bone Environment Influences Irreversible Adhesion of a Methicillin-Susceptible Strain.

Reffuveille F, Josse J, Velard F, Lamret F, Varin-Simon J, Dubus M, Haney EF, Hancock REW, Mongaret C, Gangloff SC

Front Microbiol. 2018 ;9:2865

Chemical composition, antioxidant and antibacterial activities of Tamarix balansae J. Gay aerial parts.

Benmerache A, Benteldjoune M, Alabdul Magid A, Abedini A, Berrehal D, Kabouche A, Gangloff SC, Voutquenne-Nazabadioko L, Kabouche Z

Nat. Prod. Res.. 2017 Dec;31(24):2828-2835

Collagen-Based Medical Device as a Stem Cell Carrier for Regenerative Medicine.

Aubert L, Dubus M, Rammal H, Bour C, Mongaret C, Boulagnon-Rombi C, Garnotel R, Schneider C, Rahouadj R, Laurent C, Gangloff SC, Velard F, Mauprivez C, Kerdjoudj H

Int J Mol Sci. 2017 Oct 21;18(10):

Substitution of strontium and boron into hydroxyapatite crystals: Effect on physicochemical properties and biocompatibility with human Wharton-Jelly stem cells.

Kolmas J, Velard F, Jaguszewska A, Lemaire F, Kerdjoudj H, Gangloff SC, Kaflak A

Mater Sci Eng C Mater Biol Appl. 2017 Oct 1;79:638-646

Triterpenoid saponins and other glycosides from the stems and bark of Jaffrea xerocarpa and their biological activity.

Muhammad D, Lalun N, Bobichon H, Le Magrex Debar E, Gangloff SC, Nour M, Voutquenne-Nazabadioko L

Phytochemistry. 2017 Sep;141:121-130

Abietane diterpenes from the cones of Abies numidica de Lannoy ex Carrière (Pinaceae) and in vitro evaluation of their antimicrobial properties.

Belhadj Mostefa M, Abedini A, Voutquenne-Nazabadioko L, Gangloff SC, Kabouche A, Kabouche Z

Nat. Prod. Res.. 2017 Mar;31(5):568-571

Biocompatibility of sol-gel hydroxyapatite-titania composite and bilayer coatings.

Sidane D, Rammal H, Beljebbar A, Gangloff SC, Chicot D, Velard F, Khireddine H, Montagne A, Kerdjoudj H

Mater Sci Eng C Mater Biol Appl. 2017 Mar;72:650-658

Bioinspired Nanofeatured Substrates: Suitable Environment for Bone Regeneration.

Rammal H, Dubus M, Aubert L, Reffuveille F, Laurent-Maquin D, Terryn C, Schaaf P, Alem H, Francius G, Quilès F, Gangloff SC, Boulmedais F, Kerdjoudj H

ACS Appl Mater Interfaces. 2017 Mar;:

Harnessing Wharton's jelly stem cell differentiation into bone-like nodule on calcium phosphate substrate without osteoinductive factors.

Mechiche Alami S, Rammal H, Boulagnon-Rombi C, Velard F, Lazar F, Drevet R, Laurent Maquin D, Gangloff SC, Hemmerlé J, Voegel JC, Francius G, Schaaf P, Boulmedais F, Kerdjoudj H

Acta Biomater. 2017 Feb;49:575-589

Triterpene glycosides from the aerial parts of Gouania longipetala.

Gossan DP, Alabdul Magid A, Yao-Kouassi PA, Ahibo Coffy A, Josse J, Gangloff SC, Morjani H, Voutquenne-Nazabadioko L

Phytochemistry. 2017 Feb;134:71-77

Innovative non-thermal plasma disinfection process inside sealed bags: Assessment of bactericidal and sporicidal effectiveness in regard to current sterilization norms.

Ben Belgacem Z, Carré G, Charpentier E, Le-Bras F, Maho T, Robert E, Pouvesle JM, Polidor F, Gangloff SC, Boudifa M, Gelle MP

PLoS ONE. 2017 ;12(6):e0180183

Biocompatibility study of lithium disilicate and zirconium oxide ceramics for esthetic dental abutments.

Brunot-Gohin C, Duval JL, Verbeke S, Belanger K, Pezron I, Kugel G, Laurent-Maquin D, Gangloff S, Egles C

J Periodontal Implant Sci. 2016 Dec;46(6):362-371

Strontium-Substituted Bioceramics Particles: A New Way to Modulate MCP-1 and Gro-α Production by Human Primary Osteoblastic Cells.

Braux J, Velard F, Guillaume C, Jourdain ML, Gangloff SC, Jallot E, Nedelec JM, Laquerrière P, Laurent-Maquin D

Materials (Basel). 2016 Dec;9(12):

Bio-Guided Isolation of Methanol-Soluble Metabolites of Common Spruce (Picea abies) Bark by-Products and Investigation of Their Dermo-Cosmetic Properties.

Angelis A, Hubert J, Aligiannis N, Michalea R, Abedini A, Nuzillard JM, Gangloff SC, Skaltsounis AL, Renault JH

Molecules. 2016 Nov;21(11):

Concise Review: In Vitro Formation of Bone-Like Nodules Sheds Light on the Application of Stem Cells for Bone Regeneration.

Mechiche Alami S, Gangloff SC, Laurent-Maquin D, Wang Y, Kerdjoudj H

Stem Cells Transl Med. 2016 Nov;5(11):1587-1593

In Vitro Dermo-Cosmetic Evaluation of Bark Extracts from Common Temperate Trees.

Hubert J, Angelis A, Aligiannis N, Rosalia M, Abedini A, Bakiri A, Reynaud R, Nuzillard JM, Gangloff SC, Skaltsounis AL, Renault JH

Planta Med.. 2016 Oct;82(15):1351-1358

Bioactivity-guided identification of antimicrobial metabolites in Alnus glutinosa bark and optimization of oregonin purification by Centrifugal Partition Chromatography.

Abedini A, Chollet S, Angelis A, Borie N, Nuzillard JM, Skaltsounis AL, Reynaud R, Gangloff SC, Renault JH, Hubert J

J. Chromatogr. B Analyt. Technol. Biomed. Life Sci.. 2016 Sep;1029-1030:121-7

Overexpression of RANKL in osteoblasts: a possible mechanism of susceptibility to bone disease in cystic fibrosis.

Delion M, Braux J, Jourdain ML, Guillaume C, Bour C, Gangloff S, Pimpec-Barthes FL, Sermet-Gaudelus I, Jacquot J, Velard F

J. Pathol.. 2016 Sep;240(1):50-60

Antibacterial and cytotoxic triterpenoids from the roots of Combretum racemosum.

Gossan DP, Alabdul Magid A, Yao-Kouassi PA, Josse J, Gangloff SC, Morjani H, Voutquenne-Nazabadioko L

Fitoterapia. 2016 Apr;110:89-95

Ethanolic Extract of Algerian Propolis and Galangin Decreased Murine Melanoma T.

Benguedouar L, Lahouel M, Gangloff SC, Durlach A, Grange F, Bernard P, Antonicelli F

Anticancer Agents Med Chem. 2016 ;16(9):1172-83

Impact of the Maturation of Human Primary Bone-Forming Cells on Their Behavior in Acute or Persistent Staphylococcus aureus Infection Models.

Josse J, Guillaume C, Bour C, Lemaire F, Mongaret C, Draux F, Velard F, Gangloff SC

Front Cell Infect Microbiol. 2016 ;6:64

Bone disease in cystic fibrosis: new pathogenic insights opening novel therapies.

Jacquot J, Delion M, Gangloff S, Braux J, Velard F

Osteoporos Int. 2015 Oct 2.

Potentiation of the store-operated calcium entry (SOCE) induces phytohemagglutinin-activated Jurkat T cell apoptosis.

Djillani A, Doignon I, Luyten T, Lamkhioued B, Gangloff SC, Parys JB, Nusse O, Chomienne C, Dellis O

Cell Calcium. 2015 Apr 24. pii: S0143-4160(15)00068-8

Staphylococcus aureus vs. Osteoblast: Relationship and Consequences in Osteomyelitis.

Josse J, Velard F, Gangloff SC

Front Cell Infect Microbiol. 2015 ;5:85

Cystic fibrosis bone disease: is the CFTR corrector C18 an option for therapy?

Velard F, Delion M, Lemaire F, Tabary O, Guillaume C, Le Pimpec Barthes F, Touqui L, Gangloff S, Sermet-Gaudelus I, Jacquot J

Eur Respir J. 2014 Nov 27. pii: ERJ-01740-2014.

Cystic fibrosis and bone disease: defective osteoblast maturation with the F508del mutation in cystic fibrosis transmembrane conductance regulator.

Velard F, Delion M, Le Henaff C, Guillaume C, Gangloff S, Jacquot J, Tabary O, Touqui L, Barthes F, Sermet-Gaudelus I

Am J Respir Crit Care Med. 2014 Mar 15;189(6):746-8

Chitosan/hydroxyapatite hybrid scaffold for bone tissue engineering.

Brun V, Guillaume C, Mechiche Alami S, Josse J, Jing J, Draux F, Bouthors S, Laurent-Maquin D, Gangloff SC, Kerdjoudj H, Velard F

Biomed Mater Eng. 2014;24(1 Suppl):63-73

Gene screening of Wharton's jelly derived stem cells.

Mechiche Alami S, Velard F, Draux F, Siu Paredes F, Josse J, Lemaire F, Gangloff SC, Graesslin O, Laurent-Maquin D, Kerdjoudj H

Biomed Mater Eng. 2014;24(1 Suppl):53-61

Increased internalization of Staphylococcus aureus and cytokine expression in human Wharton's jelly mesenchymal stem cells.

Josse J, Velard F, Mechiche Alami S, Brun V, Guillaume C, Kerdjoudj H, Lamkhioued B, Gangloff SC

Biomed Mater Eng. 2014;24(1 Suppl):27-35

Soft tissue adhesion of polished versus glazed lithium disilicate ceramic for dental applications.

Brunot-Gohin C, Duval JL, Azogui EE, Jannetta R, Pezron I, Laurent-Maquin D, Gangloff SC, Egles C

Dent Mater. 2013 Sep;29(9):e205-12

Rapid method of quantification of tight-junction organization using image analysis.

Terryn C, Sellami M, Fichel C, Diebold MD, Gangloff S, Le Naour R, Polette M, Zahm JM

Cytometry A. 2013 Feb;83(2):235-41

Neutrophil elastase modulates cytokine expression: contribution to host defense against Pseudomonas aeruginosa-induced pneumonia.

Benabid R, Wartelle J, Malleret L, Guyot N, Gangloff S, Lebargy F, Belaaouaj A

J Biol Chem. 2012 Oct 12;287(42):34883-94

CXCL10 reduces melanoma proliferation and invasiveness in vitro and in vivo.

Antonicelli F, Lorin J, Kurdykowski S, Gangloff SC, Le Naour R, Sallenave JM, Hornebeck W, Grange F, Bernard P

Br J Dermatol. 2011 Apr;164(4):720-8

Triterpenoid saponins from Symplocos lancifolia.

Acebey-Castellon IL, Voutquenne-Nazabadioko L, Doan Thi Mai H, Roseau N, Bouthagane N, Muhammad D, Le Magrex Debar E, Gangloff SC, Litaudon M, Sevenet T, Hung NV, Lavaud C

J Nat Prod. 2011 Feb 25;74(2):163-8