[Impact of the angles and the age of the thrombus on efficacity of thromboaspiration device. A bench study].
Fiche publication
Date publication
février 2011
Auteurs
Membres identifiés du Cancéropôle Est :
Dr GUIGNARD Marie-Hélène
Tous les auteurs :
Leromain AS, Fayard M, Lorgis L, Richard C, Zeller M, Buffet P, L'Huillier I, Guenfoudi MP, Garnier N, Guignard MH, Cottin Y
Lien Pubmed
Résumé
INTRODUCTION: Coronary thrombectomy is usually used to treat acute coronary syndrome. Many studies evaluated its benefit in this context however, it is still unknown if coronary characteristics are predictive of success or failure. The aim of our laboratory bench study was to evaluate the impact of angiographic characteristics on the thromboaspiration efficiency. METHODS: Glass tubes of 150 mm in the length were used, with five diameters: 2; 2.6; 3; 3.6 and 4 mm; and for each diameter, three angulations: no angulation; 90 degrees and 120 degrees . Blood sample were taken from healthy subject and thrombi of 3 and 6 hours old were performed, with a constant volume for each test. Thromboaspirations were performed with an Export((R)) catheter (Medtronic). The primary endpoint was total thrombectomy. A total of 240 thromboaspirations were performed. RESULTS: A total thrombectomy was obtained for 71.2% of the tests. It was achieved more frequently with the smaller diameter, respectively: 100% for 2 mm, 81.3% for 2.6 mm, 89.6% for 3 mm vs 54.2% for 3.6 mm and 31.3% for 4 mm (P
Référence
Ann Cardiol Angeiol (Paris). 2011 Feb;60(1):9-14