[Pathophysiology of immune thrombocytopenia].
Fiche publication
Date publication
juin 2011
Auteurs
Membres identifiés du Cancéropôle Est :
Pr BONNOTTE Bernard
Tous les auteurs :
Audia S, Lorcerie B, Godeau B, Bonnotte B
Lien Pubmed
Résumé
Immune thrombocytopenia is an autoimmune disease characterized by a peripheral destruction of platelets. B lymphocytes play a key role but pathogenesis is more complex, involving humoral and cellular immunity associated with an inappropriate platelet production. In this article, we review the different pathogenic pathways, leading to new therapeutic strategies.
Référence
Rev Med Interne. 2011 Jun;32(6):350-7