IAPs and cell migration.
Fiche publication
Date publication
mars 2015
Journal
Seminars in cell & developmental biology
Auteurs
Membres identifiés du Cancéropôle Est :
Dr DUBREZ Laurence
Tous les auteurs :
Dubrez L, Rajalingam K
Lien Pubmed
Résumé
Inhibitors of apoptosis (IAPs) constitute a family of cell signaling regulators controlling several fundamental biological processes such as innate immunity, inflammation, cell death, cell proliferation, and cell differentiation. Increasing evidence from in vivo and in vitro studies indicate a function for IAPs in the modulation of invasive and migratory properties of cells. Here, we present and discuss the mechanisms whereby IAPs can control cell migration.
Mots clés
Animals, Cell Adhesion, Cell Movement, Cytoskeleton, metabolism, Humans, Inhibitor of Apoptosis Proteins, metabolism, Signal Transduction
Référence
Semin. Cell Dev. Biol.. 2015 Mar;39:124-31