Effects of Maternal Linseed Oil Supplementation on Metabolic Parameters in Cafeteria Diet-induced Obese Rats.
Fiche publication
Date publication
avril 2015
Journal
Biomedical and environmental sciences : BES
Auteurs
Membres identifiés du Cancéropôle Est :
Pr NARCE Michel
Tous les auteurs :
Benaissa N, Merzouk H, Merzouk SA, Narce M
Lien Pubmed
Résumé
Because linseed oil may influence maternal and fetal metabolisms, we investigated its role in the modulation of lipid metabolism in cafeteria diet-induced obese rats and their offspring. Female Wistar rats were fed control or cafeteria food, which were either supplemented or not supplemented with linseed oil (5%) for 1 month before and during gestation. At parturition, serum and tissue lipids and enzyme activities were analyzed. Cafeteria diet induced adverse metabolic alterations in both mothers and offspring. Linseed oil improved metabolic status. In conclusion, linseed oil displayed health benefits by modulating tissue enzyme activities in both obese mothers and their newborns.
Mots clés
Animal Feed, analysis, Animals, Diet, adverse effects, Dietary Supplements, analysis, Female, Linseed Oil, administration & dosage, Lipid Metabolism, drug effects, Maternal Nutritional Physiological Phenomena, drug effects, Obesity, drug therapy, Pregnancy, Prenatal Exposure Delayed Effects, drug therapy, Random Allocation, Rats, Rats, Wistar
Référence
Biomed. Environ. Sci.. 2015 Apr;28(4):298-302