Healing of diabetic foot ulcers is independently associated with the use of angiotensin receptor blockers but not with those of diuretics and angiotensin conversion enzyme inhibitors.
Fiche publication
Date publication
mars 2022
Journal
Diabetes & metabolism
Auteurs
Membres identifiés du Cancéropôle Est :
Pr PETIT Jean-Michel, Pr VERGES Bruno
Tous les auteurs :
Lapray M, Petit JM, Fourmont C, Rouland A, Vergès B, Bouillet B
Lien Pubmed
Résumé
Dysregulation of the renin angiotensin system (RAS) has been proven in diabetic animal models, and studies in humans show that diuretic use is associated with lower limb amputation in diabetes. While patients with diabetes are often treated with diuretics and RAS blockers, the association between wound healing and these treatments is still unknown. We aimed to determine whether the use of diuretics and RAS blockers could influence healing of diabetic foot ulcers (DFU).
Mots clés
Angiotensin conversion enzyme inhibitors, Angiotensin receptor blockers, Diabetes mellitus, Diabetic foot ulcer, Diuretics, Healing
Référence
Diabetes Metab. 2022 Mar 1;:101336