Impact of repeated measures of joint space width on the sample size calculation: An application to hip osteoarthritis.
Fiche publication
Date publication
mai 2015
Journal
Joint bone spine
Auteurs
Membres identifiés du Cancéropôle Est :
Pr ORNETTI Paul
Tous les auteurs :
Ornetti P, Gossec L, Laroche D, Combescure C, Dougados M, Maillefert JF
Lien Pubmed
Résumé
The aims of the study were to investigate the impact of aggregation of repeated readings (a) on minimising variability of joint space width (JSW) measurements based on calculation of the smallest detectable difference (SDD) and (b) on sample size calculation in a hip OA randomized controlled trial (RCT).
Mots clés
Hip, Joint space, Osteoarthritis, Randomized clinical trial, Sample size, Smallest detectable difference
Référence
Joint Bone Spine. 2015 May;82(3):172-6