Effect of short-term exercise training on brain-derived neurotrophic factor signaling in spontaneously hypertensive rats.
Fiche publication
Date publication
février 2017
Journal
Journal of hypertension
Auteurs
Membres identifiés du Cancéropôle Est :
Mr PERNET Nicolas
Tous les auteurs :
Monnier A, Garnier P, Quirie A, Pernet N, Demougeot C, Marie C, Prigent-Tessier A
Lien Pubmed
Résumé
Decreased brain-derived neurotrophic factor (BDNF) level has been reported in the hippocampus of hypertensive rats. The present study explored whether brain neurons and/or endothelial cells are targeted by hypertension with respect to BDNF expression and the potential of physical exercise to cope with hypertension.
Mots clés
Animals, Blood Pressure, Brain-Derived Neurotrophic Factor, metabolism, Endothelial Cells, metabolism, Hippocampus, metabolism, Hypertension, metabolism, Neurons, metabolism, Nitric Oxide, metabolism, Nitric Oxide Synthase Type III, metabolism, Nitroglycerin, pharmacology, Phosphorylation, Physical Conditioning, Animal, physiology, Protein Precursors, metabolism, Protein-Tyrosine Kinases, metabolism, Rats, Rats, Inbred SHR, Rats, Inbred WKY, Receptor, trkB, Signal Transduction, Synaptophysin, metabolism, Vasodilator Agents, pharmacology
Référence
J Hypertens. 2017 02;35(2):279-290