Impact of open-label versus blinded study design on patient-reported outcomes data in randomized clinical trials of immunotherapy in advanced or metastatic cancer patients: a systematic review.
Fiche publication
Date publication
juillet 2021
Journal
Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation
Auteurs
Membres identifiés du Cancéropôle Est :
Pr WESTEEL Virginie, Mme POZET Astrid, Dr MOUILLET Guillaume
Tous les auteurs :
Anota A, Pozet A, Lemasson H, Cotté FE, Falcoz A, Eberst G, Mouillet G, Guerzider S, Charton É, Westeel V
Lien Pubmed
Résumé
A systematic literature review of immuno-oncology trials was conducted to assess the potential impact of open-label vs double-blind trial design on patient-reported outcome (PRO) data.
Mots clés
Bias, Immuno-oncology, Open label, Patient-reported outcomes, Quality of life, Randomized controlled trials
Référence
Qual Life Res. 2021 Jul 20;: