Tolerance and Effectiveness of Targeted Therapies in Aged Patients with Metastatic Melanoma.

Fiche publication


Date publication

juin 2021

Journal

Cancers

Auteurs

Membres identifiés du Cancéropôle Est :
Pr AUBIN François, Dr DALAC Sophie


Tous les auteurs :
Becquart O, Oriano B, Dalle S, Mortier L, Leccia MT, Dutriaux C, Dalac S, Montaudié H, De Quatrebarbes J, Brunet-Possenti F, Saiag P, Lesimple T, Beylot-Barry M, Aubin F, Stoebner PE, Arnault JP, Dreno B, Porcher R, Lebbe C, Guillot B

Résumé

Melanoma's incidence is increasing, and elderly people could be significantly impacted since the majority occurs in people over 65 years of age. Combined BRAF and MEK targeted therapies (TT) are current standard regimen for BRAF mutated metastatic melanoma (MM). Except for subgroups of pivotal trials, little data are available for TT in this population.

Mots clés

elderly people, melanoma, side effects, targeted therapy

Référence

Cancers (Basel). 2021 Jun 18;13(12):