Atypical hemolytic and uremic syndrome due to C3 mutation in pancreatic islet transplantation: a case report.
Fiche publication
Date publication
septembre 2020
Journal
BMC nephrology
Auteurs
Membres identifiés du Cancéropôle Est :
Pr CHENARD Marie-Pierre, Dr BALTZINGER Philippe
Tous les auteurs :
Bahougne T, Olagne J, Munch M, Braun-Parvez L, Chenard MP, Frémeaux-Bacchi V, Caillard S, Baltzinger P, Greget M, Kessler L, Moulin B
Lien Pubmed
Résumé
We here report on the first observation of a C3 mutation that is related to atypical hemolytic and uremic syndrome (aHUS), which occurred in a pancreatic islet transplant patient. Immunosuppressive treatments, such as calcineurin inhibitors, have been linked to undesirable effects like nephrotoxicity.
Mots clés
Atypical hemolytic and uremic syndrome, Case report, Complement C3, Islets of Langerhans transplantation
Référence
BMC Nephrol. 2020 Sep 19;21(1):405