Systemic lupus erythematosus and neutropaenia: a hallmark of haematological manifestations.
Fiche publication
Date publication
juillet 2020
Journal
Lupus science & medicine
Auteurs
Membres identifiés du Cancéropôle Est :
Pr BONNOTTE Bernard, Pr MARTIN Thierry
Tous les auteurs :
Meyer A, Guffroy A, Blaison G, Dieudonne Y, Amoura Z, Bonnotte B, Fiehn C, Kieffer P, Lorenz HM, Magy-Bertrand N, Maurier F, Pennaforte JL, Peter HH, Schwarting A, Sibilia J, Arnaud L, Martin T, Voll RE, Korganow AS,
Lien Pubmed
Résumé
Systemic lupus is a chronic autoimmune disease characterised by its phenotypic heterogeneity. Neutropaenia is a frequent event in SLE occurring in 20%-40% of patients depending on the threshold value of neutrophil count. On a daily basis, the management of neutropaenia in SLE is difficult with several possible causes. Moreover, the infectious consequences of neutropaenia in SLE remain not well defined.
Mots clés
autoantibodies, autoimmune diseases, lupus erythematosus, systemic
Référence
Lupus Sci Med. 2020 Jul;7(1):