Event-Related Potentials (ERP) Indices of Motivation during the Effort Expenditure for Reward Task.
Fiche publication
Date publication
mai 2020
Journal
Brain sciences
Auteurs
Membres identifiés du Cancéropôle Est :
Dr PAZART Lionel, Pr HAFFEN Emmanuel, Pr TROJAK Benoît
Tous les auteurs :
Giustiniani J, Nicolier M, Teti Mayer J, Chabin T, Masse C, Galmès N, Pazart L, Trojak B, Bennabi D, Vandel P, Haffen E, Gabriel D
Lien Pubmed
Résumé
Dynamic and temporal facets of the various constructs that comprise motivation remain to be explored. Here, we adapted the Effort Expenditure for Reward Task, a well-known laboratory task used to evaluate motivation, to study the event-related potentials associated with reward processing. The Stimulus Preceding Negativity (SPN) and the P300 were utilized as motivation indicators with high density electroencephalography. The SPN was found to be more negative for difficult choices compared to easy choices, suggesting a greater level of motivation, at a neurophysiological level. The insula, a structure previously associated with both effort discounting and prediction error, was concomitantly activated during the generation of the SPN. Processing a gain significantly altered the amplitude of the P300 compared to an absence of gain, particularly on centroparietal electrodes. One of the generators of the P300 was located on the vmPFC, a cerebral structure involved in the choice between two positive results and their predictions, during loss processing. Both the SPN and the P300 appear to be reliable neural markers of motivation. We postulate that the SPN represents the strength of the motivational level, while the P300 represents the impact of motivation on updating memories of the feedback.
Mots clés
EEfRT, P300, SPN, effort, motivation
Référence
Brain Sci. 2020 May 8;10(5):