Efficacy and Safety of Adjuvant Proton Therapy Combined With Surgery for Chondrosarcoma of the Skull Base: A Retrospective, Population-Based Study.
Fiche publication
Date publication
mai 2016
Journal
International journal of radiation oncology, biology, physics
Auteurs
Membres identifiés du Cancéropôle Est :
Pr NOEL Georges
Tous les auteurs :
Feuvret L, Bracci S, Calugaru V, Bolle S, Mammar H, De Marzi L, Bresson D, Habrand JL, Mazeron JJ, Dendale R, Noël G
Lien Pubmed
Résumé
Chondrosarcoma is a rare malignant tumor of the cartilage affecting young adults. Surgery, followed by charged-particle irradiation, is considered the reference standard for the treatment of patients with grade I to II skull base chondrosarcoma. The present study was conducted to assess the effect of the quality of surgery and radiation therapy parameters on local control (LC) and overall survival (OS).
Mots clés
Adolescent, Adult, Aged, Aged, 80 and over, Child, Chondrosarcoma, mortality, Follow-Up Studies, Humans, Middle Aged, Neoplasm Recurrence, Local, Organ Sparing Treatments, Organs at Risk, Photons, therapeutic use, Proton Therapy, adverse effects, Radiotherapy, Adjuvant, adverse effects, Relative Biological Effectiveness, Retrospective Studies, Skull Base Neoplasms, mortality, Survival Rate, Time Factors, Tumor Burden
Référence
Int. J. Radiat. Oncol. Biol. Phys.. 2016 May;95(1):312-21